Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.46 |
| ▸ | JAK1 | P23458 | 2/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3001224 | 0.89 | HSD11B1 (0.47) | NR1H2HSD11B1GPR119MEN1KMT2A | |
| SCHEMBL29138582 | 0.82 | HSD11B1 (0.61) | HSD11B1USP30GPR119MEN1KMT2A | |
| SCHEMBL31736852 | 0.82 | GPR119 (0.57) | HSD11B1GPR119MEN1KMT2AUSP2 | |
| SCHEMBL29138599 | 0.79 | OXTR (0.48) | NR1H2HSD11B1GPR119MEN1KMT2A | |
| SCHEMBL29228600 | 0.78 | NR1H2 (0.51) | NR1H2HSD11B1JAK1KCNK3KCNK9 | |
| SCHEMBL2995952 | 0.77 | GPR119 (0.47) | NR1H2HSD11B1GPR119HPGDKDM4E | |
| SCHEMBL30639344 | 0.77 | GPR119 (0.46) | GPR119MEN1KMT2AUSP2HPGD | |
| SCHEMBL30639343 | 0.77 | GPR119 (0.46) | GPR119MEN1KMT2AUSP2HPGD | |
| SCHEMBL25296230 | 0.76 | GPR119 (0.43) | NR1H2USP30GPR119HPGDKDM4E | |
| SCHEMBL22412769 | 0.76 | GPR119 (0.43) | NR1H2HSD11B1GPR119HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247395-A | PDE4B inhibitors | 武汉人福创新药物研发中心有限公司 | 2023-12-19 | — | — | CN | disclosed |