Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29138822 | 1.00 | PRKCZ (0.34) | PRKCZHTR2CLMNAGAAL3MBTL1 | |
| SCHEMBL29138868 | 1.00 | PRKCZ (0.34) | PRKCZHTR2CLMNAGAAL3MBTL1 | |
| SCHEMBL10345879 | 0.80 | CHRNB2 (0.35) | MEN1KMT2A | |
| SCHEMBL28148132 | 0.78 | PDE2A (0.40) | PRKCZHTR2CMEN1KMT2A | |
| SCHEMBL29236303 | 0.77 | PDE2A (0.41) | PRKCZHTR2CMEN1KMT2A | |
| SCHEMBL29138927 | 0.74 | HTR2C (0.43) | HTR2C | |
| SCHEMBL29138796 | 0.74 | AKR1C3 (0.39) | HTR2CLMNA | |
| SCHEMBL29138918 | 0.74 | AKR1C3 (0.39) | HTR2CLMNA | |
| SCHEMBL29138924 | 0.74 | HTR2C (0.43) | HTR2C | |
| SCHEMBL29138870 | 0.74 | AKR1C3 (0.39) | HTR2CLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116888120-A | PRMTS inhibitors | 美国安进公司 | 2023-10-13 | — | — | CN | disclosed |