Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | F2R | P25116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29138870 | 1.00 | AKR1C3 (0.39) | AKR1C3HIF1AEPAS1PDE2AEPHX2 | |
| SCHEMBL29138796 | 1.00 | AKR1C3 (0.39) | AKR1C3HIF1AEPAS1PDE2AEPHX2 | |
| Trifluoroacetic Acid SCHEMBL29138866 | 0.92 | AKR1C3 (0.40) | AKR1C3HIF1AEPAS1EPHX2F2R | |
| SCHEMBL29138909 | 0.92 | EPHX2 (0.36) | AKR1C3HIF1AEPAS1PDE2AEPHX2 | |
| SCHEMBL29138883 | 0.92 | EPHX2 (0.36) | AKR1C3HIF1AEPAS1PDE2AEPHX2 | |
| SCHEMBL29138867 | 0.89 | MLYCD (0.32) | HDAC1HDAC8HDAC6 | |
| SCHEMBL29138862 | 0.84 | HDAC1 (0.38) | AKR1C3KDM4EALDH1A1SMN1; SMN2HDAC1 | |
| SCHEMBL29138873 | 0.82 | PRKDC (0.41) | EPHX2 | |
| SCHEMBL29138877 | 0.82 | PRKDC (0.41) | EPHX2 | |
| SCHEMBL29138869 | 0.80 | HIF1A (0.39) | AKR1C3HIF1AEPAS1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116888120-A | PRMTS inhibitors | 美国安进公司 | 2023-10-13 | — | — | CN | disclosed |