Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | LGMN | Q99538 | 1/20 | 0.37 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29138877 | 1.00 | PRKDC (0.41) | PRKDCEPHX2HCRTR1HCRTR2LGMN | |
| SCHEMBL29138870 | 0.82 | AKR1C3 (0.39) | EPHX2 | |
| SCHEMBL29138918 | 0.82 | AKR1C3 (0.39) | EPHX2 | |
| SCHEMBL29138796 | 0.82 | AKR1C3 (0.39) | EPHX2 | |
| SCHEMBL29138853 | 0.82 | GRM2 (0.37) | PRKDCEPHX2PIK3C3 | |
| SCHEMBL29138818 | 0.82 | GRM2 (0.37) | PRKDCEPHX2PIK3C3 | |
| SCHEMBL29138847 | 0.82 | ALDH1A1 (0.39) | MAPTPKM | |
| SCHEMBL29138888 | 0.82 | ALDH1A1 (0.39) | MAPTPKM | |
| SCHEMBL29138862 | 0.80 | HDAC1 (0.38) | PRKDCMAPT | |
| SCHEMBL29138867 | 0.80 | MLYCD (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116888120-A | PRMTS inhibitors | 美国安进公司 | 2023-10-13 | — | — | CN | disclosed |