Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.34 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.34 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29138864 | 1.00 | AR (0.36) | ARNOTUMGRIN2BABCC9ABCC8 | |
| SCHEMBL29138818 | 0.82 | GRM2 (0.37) | PIK3C3ALDH1A1AKT1EPHX2 | |
| SCHEMBL29138853 | 0.82 | GRM2 (0.37) | PIK3C3ALDH1A1AKT1EPHX2 | |
| SCHEMBL29138918 | 0.80 | AKR1C3 (0.39) | ALDH1A1HDAC1HDAC8HDAC6EPHX2 | |
| SCHEMBL29138870 | 0.80 | AKR1C3 (0.39) | ALDH1A1HDAC1HDAC8HDAC6EPHX2 | |
| SCHEMBL29138796 | 0.80 | AKR1C3 (0.39) | ALDH1A1HDAC1HDAC8HDAC6EPHX2 | |
| SCHEMBL29138862 | 0.78 | HDAC1 (0.38) | ALDH1A1HDAC1HDAC8HDAC6 | |
| SCHEMBL29138881 | 0.77 | HDAC4 (0.36) | PIK3CAMTORHDAC1HDAC8HDAC6 | |
| SCHEMBL29138880 | 0.77 | HDAC4 (0.36) | PIK3CAMTORHDAC1HDAC8HDAC6 | |
| SCHEMBL29138867 | 0.75 | MLYCD (0.32) | HDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116888120-A | PRMTS inhibitors | 美国安进公司 | 2023-10-13 | — | — | CN | disclosed |