Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 10/20 | 0.33 |
| ▸ | RAF1 | P04049 | 9/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | MTOR | P42345 | 2/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29138881 | 1.00 | HDAC4 (0.36) | HDAC4HDAC8HDAC6HDAC1BRAF | |
| SCHEMBL29138907 | 0.81 | HRH3 (0.37) | HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL29138870 | 0.77 | AKR1C3 (0.39) | HDAC8HDAC6HDAC1 | |
| SCHEMBL29138796 | 0.77 | AKR1C3 (0.39) | HDAC8HDAC6HDAC1 | |
| SCHEMBL29138918 | 0.77 | AKR1C3 (0.39) | HDAC8HDAC6HDAC1 | |
| SCHEMBL29138891 | 0.77 | AR (0.36) | HDAC8HDAC6HDAC1PIK3CAMTOR | |
| SCHEMBL29138864 | 0.77 | AR (0.36) | HDAC8HDAC6HDAC1PIK3CAMTOR | |
| SCHEMBL29138795 | 0.75 | ATM (0.31) | HDAC8HDAC6HDAC1PIK3CAMTOR | |
| SCHEMBL29138862 | 0.72 | HDAC1 (0.38) | HDAC8HDAC6HDAC1 | |
| SCHEMBL28818473 | 0.71 | HDAC4 (0.45) | HDAC4LOXL2CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116888120-A | PRMTS inhibitors | 美国安进公司 | 2023-10-13 | — | — | CN | disclosed |