Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | XPO1 | O14980 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29138869 | 0.77 | HIF1A (0.39) | KDM4EMAPTSMN1; SMN2FGFR4ABL1 | |
| SCHEMBL29138900 | 0.77 | HIF1A (0.39) | KDM4EMAPTSMN1; SMN2FGFR4ABL1 | |
| SCHEMBL31424110 | 0.72 | KDM4E (0.34) | KDM4EMAPTSMN1; SMN2ALDH1A1APAF1 | |
| SCHEMBL31424096 | 0.72 | LIPE (0.39) | KDM4EMAPTSMN1; SMN2ALDH1A1APAF1 | |
| SCHEMBL24540721 | 0.69 | NPSR1 (0.34) | KDM4EALDH1A1LMNANPSR1 | |
| SCHEMBL29651037 | 0.69 | NPSR1 (0.34) | KDM4EALDH1A1LMNANPSR1 | |
| Hydrochloric Acid SCHEMBL31137617 | 0.68 | NPSR1 (0.33) | KDM4EALDH1A1LMNANPSR1 | |
| SCHEMBL6903019 | 0.68 | MTOR (0.40) | KDM4EMAPTSMN1; SMN2ALDH1A1APAF1 | |
| SCHEMBL31017227 | 0.68 | KDM4E (0.35) | KDM4EMAPTSMN1; SMN2ALDH1A1APAF1 | |
| SCHEMBL29138936 | 0.66 | PDE9A (0.41) | KDM4EMAPTSMN1; SMN2ALDH1A1APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116888120-A | PRMTS inhibitors | 美国安进公司 | 2023-10-13 | — | — | CN | disclosed |