Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.33 |
| ▸ | PDE2A | O00408 | 3/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29138880 | 0.81 | HDAC4 (0.36) | HDAC6HDAC8HDAC1HDAC4 | |
| SCHEMBL29138881 | 0.81 | HDAC4 (0.36) | HDAC6HDAC8HDAC1HDAC4 | |
| SCHEMBL29138795 | 0.81 | ATM (0.31) | KCNH2HDAC6HDAC8HDAC1 | |
| SCHEMBL5320247 | 0.81 | AKR1C3 (0.38) | — | |
| SCHEMBL29138796 | 0.80 | AKR1C3 (0.39) | HDAC6HDAC8HDAC1PDE2A | |
| SCHEMBL29138918 | 0.80 | AKR1C3 (0.39) | HDAC6HDAC8HDAC1PDE2A | |
| SCHEMBL29138870 | 0.80 | AKR1C3 (0.39) | HDAC6HDAC8HDAC1PDE2A | |
| SCHEMBL29138812 | 0.77 | HCRTR1 (0.33) | HDAC6 | |
| SCHEMBL29138817 | 0.77 | HCRTR1 (0.33) | HDAC6 | |
| SCHEMBL29138862 | 0.76 | HDAC1 (0.38) | HDAC6HDAC8HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116888120-A | PRMTS inhibitors | 美国安进公司 | 2023-10-13 | — | — | CN | disclosed |