Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.34 |
| ▸ | F2R | P25116 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29138883 | 1.00 | EPHX2 (0.36) | EPHX2AKR1C3PDE2AHIF1AEPAS1 | |
| SCHEMBL29138870 | 0.92 | AKR1C3 (0.39) | EPHX2AKR1C3PDE2AHIF1AEPAS1 | |
| SCHEMBL29138796 | 0.92 | AKR1C3 (0.39) | EPHX2AKR1C3PDE2AHIF1AEPAS1 | |
| SCHEMBL29138918 | 0.92 | AKR1C3 (0.39) | EPHX2AKR1C3PDE2AHIF1AEPAS1 | |
| Trifluoroacetic Acid SCHEMBL29138866 | 0.85 | AKR1C3 (0.40) | EPHX2AKR1C3HIF1AEPAS1F2R | |
| SCHEMBL28148132 | 0.81 | PDE2A (0.40) | PDE2AKMT2AMEN1HPGDTSHR | |
| SCHEMBL29138867 | 0.81 | MLYCD (0.32) | — | |
| SCHEMBL29236303 | 0.80 | PDE2A (0.41) | PDE2AKMT2AMEN1HPGDTSHR | |
| SCHEMBL29138862 | 0.76 | HDAC1 (0.38) | AKR1C3KMT2A | |
| SCHEMBL29138873 | 0.75 | PRKDC (0.41) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116888120-A | PRMTS inhibitors | 美国安进公司 | 2023-10-13 | — | — | CN | disclosed |