Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CASP6 | P55212 | 2/20 | 0.33 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.33 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25337616 | 0.82 | PNMT (0.41) | PNMTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL6256393 | 0.81 | PGR (0.43) | PNMTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL29177673 | 0.79 | PGR (0.42) | PNMTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL30103698 | 0.79 | PGR (0.42) | PNMTNPC1RAB9AALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL27407138 | 0.79 | PGR (0.42) | PNMTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL28214865 | 0.78 | NPC1 (0.43) | PNMTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL20502811 | 0.78 | PGR (0.38) | PNMTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL22289807 | 0.78 | NPC1 (0.44) | PNMTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL22157598 | 0.77 | NPC1 (0.42) | PNMTNPC1RAB9AALDH1A1KDM4E | |
| Ammonia Solution, Strong SCHEMBL31203581 | 0.77 | NPC1 (0.42) | PNMTNPC1RAB9AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116789883-B | Polyolefin elastomer and application thereof in photovoltaic packaging film | 万华化学集团股份有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-116789883-A | Polyolefin elastomer and application thereof in photovoltaic packaging film | 万华化学集团股份有限公司 | 2023-09-22 | — | — | CN | disclosed |