SCHEMBL291397

SCHEMBL291397

CC(C)C(C)(C(=O)NCCO)C(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
USP2 O75604 1/20 0.41
MAPT P10636 1/20 0.41
CNR1 P21554 3/20 0.37
TDP1 Q9NUW8 1/20 0.36
CYP3A4 P08684 1/20 0.36
TSHR P16473 1/20 0.36
CHRNB2 P17787 1/20 0.36
CHRNB4 P30926 1/20 0.36
CHRNA3 P32297 1/20 0.36
CHRNA4 P43681 1/20 0.36
PTGS1 P23219 1/20 0.35
KCNH2 Q12809 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
CA14 Q9ULX7 1/20 0.33
RAB9A P51151 1/20 0.33
POLB P06746 1/20 0.32
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5836968 0.88 PTGS1 (0.49) ALDH1A1MEN1KMT2ACNR1TDP1
SCHEMBL12449353 0.83 KDM4C (0.42) ALDH1A1MEN1KMT2ACHRNB2CHRNB4
SCHEMBL14108227 0.83 ALDH1A1 (0.41) ALDH1A1MEN1KMT2AUSP2MAPT
SCHEMBL14889325 0.82 TSHR (0.47) ALDH1A1KMT2ATDP1TSHRSMN1; SMN2
SCHEMBL5807533 0.82 PIK3CD (0.33) ALDH1A1USP2MAPTTDP1TSHR
SCHEMBL11337132 0.82 CNR1 (0.38) ALDH1A1MEN1KMT2AUSP2MAPT
SCHEMBL12565674 0.81 ALDH1A1 (0.42) ALDH1A1MEN1KMT2AUSP2MAPT
SCHEMBL300067 0.81 CNR1 (0.32) CNR1CNR2
SCHEMBL18287157 0.81 ANPEP (0.42) MEN1KMT2ACNR1SMN1; SMN2RAB9A
SCHEMBL19944347 0.79 HPGD (0.45) ALDH1A1MEN1KMT2ACA14POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 380 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583718-A1 FLAVONOID COMPOSITIONS AND USES THEREOF Firmenich SA (CH) 2025-07-16 EP claimed
WO-2025132323-A1 COMPOSITIONS COMPRISING A SUNSCREEN ACTIVE AGENT DSM-FIRMENICH AG (CH) 2025-06-26 WO claimed
CN-120129464-A Flavonoid compound and application thereof 弗门尼舍有限公司 2025-06-10 CN claimed
EP-4251122-B1 COMPOSITIONS THAT ENHANCE THE COOLING EFFECT FIRMENICH INCORPORATED (US) 2025-03-12 EP claimed
US-20240238183-A1 COMPOSITIONS THAT ENHANCE THE COOLING EFFECT FIRMENICH INCORPORATED (US) 2024-07-18 US claimed
WO-2024088925-A1 FLAVONOID COMPOSITIONS AND USES THEREOF FIRMENICH SA (CH) 2024-05-02 WO claimed
US-20240058238-A1 COMPOSITIONS THAT ENHANCE THE COOLING EFFECT FIRMENICH INCORPORATED (US) 2024-02-22 US claimed
US-20240058259-A1 COMPOSITIONS COMPRISING ESSENTIAL OILS FIRMENICH SA (CH) 2024-02-22 US claimed
CN-117479843-A Composition for enhancing cooling effect 弗门尼舍公司 2024-01-30 CN claimed
EP-4304385-A1 COMPOSITIONS THAT ENHANCE THE COOLING EFFECT Firmenich Incorporated (US) 2024-01-17 EP claimed
WO-2013079349-A1 COSMETIC AEROSOL SPRAY WITH LASTING FRESHNESS EFFECT HENKEL AG & CO. KGAA (DE) 2013-06-06 WO claimed
EP-2079321-B1 COOLING CONFECTIONERIES AND BEVERAGES KRAFT FOODS GLOBAL BRANDS LLC (US) 2013-05-01 EP claimed
WO-2013041611-A1 WATER-FREE FORMULATIONS HAVING A COOLING EFFECT HENKEL AG & CO. KGAA (DE) 2013-03-28 WO claimed
US-20120095042-A1 Organic Compounds Having Cooling Properties GIVAUDAN SA (CH) 2012-04-19 US claimed
EP-2427170-A2 ORGANIC COMPOUNDS HAVING COOLING PROPERTIES Givaudan SA (CH) 2012-03-14 EP claimed
US-20110159141-A1 COOLING CONFECTIONERIES AND BEVERAGES INTERCONTINENTAL GREAT BRANDS LLC 2011-06-30 US claimed
WO-2010128026-A2 ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2010-11-11 WO claimed
EP-2079321-A1 COOLING CONFECTIONERIES AND BEVERAGES Cadbury Adams USA LLC (US) 2009-07-22 EP claimed
US-20080293821-A1 Cooling compositions MOZA ASHOK K 2008-11-27 US claimed
WO-2008039522-A1 COOLING CONFECTIONERIES AND BEVERAGES CADBURY ADAMS USA LLC (US) 2008-04-03 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120095042-A1 Organic Compounds Having Cooling Properties ME3, ME2, MSMO1 ALDH1A1 748/4885MEN1 133/4885KMT2A 2421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.