SCHEMBL29142174

SCHEMBL29142174

OCCNCc1c[c]cnc1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.38
GSR P00390 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
PDCD1 Q15116 4/20 0.35
CD274 Q9NZQ7 4/20 0.35
ALDH1A1 P00352 2/20 0.33
TSHR P16473 1/20 0.33
NPSR1 Q6W5P4 1/20 0.30
SCN8A Q9UQD0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3666063 0.81 SMN1; SMN2 (0.51) SMN1; SMN2PDCD1CD274ALDH1A1TSHR
SCHEMBL3666546 0.77 PRMT6 (0.48) SMN1; SMN2PDCD1CD274SCN8A
SCHEMBL7652647 0.75 GSR (0.46) CHRM2GSRSMN1; SMN2CYP1A2CYP2D6
SCHEMBL30635465 0.75 CHRM2 (0.43) CHRM2GSRSMN1; SMN2CYP1A2CYP2D6
SCHEMBL28152344 0.75
SCHEMBL3667596 0.72 MEN1 (0.43) CHRM2SMN1; SMN2PDCD1CD274ALDH1A1
SCHEMBL4051279 0.70 CYP1A2 (0.74) CHRM2SMN1; SMN2CYP1A2CYP2D6ALDH1A1
SCHEMBL29870183 0.70 CYP1A2 (0.74) CHRM2SMN1; SMN2CYP1A2CYP2D6ALDH1A1
SCHEMBL3516514 0.70 NPSR1 (0.43) SMN1; SMN2ALDH1A1NPSR1
Hydrochloric Acid SCHEMBL6264264 0.69 CYP1A2 (0.71) CHRM2CYP1A2CYP2D6ALDH1A1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117083279-A Oxazepine compounds and their use in the treatment of cancer 基因泰克公司 2023-11-17 CN disclosed