Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | CA12 | O43570 | 3/20 | 0.52 |
| ▸ | CA3 | P07451 | 3/20 | 0.52 |
| ▸ | CA4 | P22748 | 3/20 | 0.52 |
| ▸ | CA6 | P23280 | 3/20 | 0.52 |
| ▸ | CA5A | P35218 | 3/20 | 0.52 |
| ▸ | CA7 | P43166 | 3/20 | 0.52 |
| ▸ | CA9 | Q16790 | 3/20 | 0.52 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3254088 | 0.82 | ALDH1A1 (0.59) | ALDH1A1CYP3A4MAPK1NPC1CA1 | |
| SCHEMBL426162 | 0.81 | ALDH1A1 (0.52) | ALDH1A1CYP3A4MAPK1NPC1CA1 | |
| SCHEMBL8789025 | 0.80 | ALDH1A1 (0.56) | ALDH1A1CYP3A4MAPK1NPC1CA1 | |
| SCHEMBL198600 | 0.80 | PSIP1 (0.58) | ALDH1A1CYP3A4MAPK1NPC1CA1 | |
| SCHEMBL3412353 | 0.78 | ALDH1A1 (0.54) | ALDH1A1CYP3A4MAPK1NPC1CA1 | |
| SCHEMBL11375991 | 0.78 | GAA (0.61) | ALDH1A1CYP3A4CA1CA2CA12 | |
| SCHEMBL1595559 | 0.78 | CA2 (0.45) | ALDH1A1CYP3A4NPC1CA1CA2 | |
| SCHEMBL5720555 | 0.78 | ALDH1A1 (0.54) | ALDH1A1CYP3A4MAPK1NPC1CA1 | |
| SCHEMBL6219614 | 0.78 | ALDH1A1 (0.54) | ALDH1A1CYP3A4MAPK1NPC1CA1 | |
| SCHEMBL11666329 | 0.78 | CA2 (0.57) | ALDH1A1CYP3A4NPC1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963337-B1 | THIENO[2,3-b]PYRIDINE DERIVATIVES | RICHTER GEDEON NYRT (HU) | 2010-09-01 | — | — | EP | disclosed |
| US-20100022521-A1 | COMPOUNDS | HANSA METALLWERKE AG (DE) | 2010-01-28 | — | — | US | disclosed |
| CN-101341152-A | Novel compounds | RICHTER GEDEON NYRT (HU) | 2009-01-07 | — | — | CN | disclosed |
| EP-1963337-A1 | NEW COMPOUNDS | Richter Gedeon NYRT (HU) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007072095-A1 | NEW COMPOUNDS | RICHTER GEDEON NYRT. (HU) | 2007-06-28 | — | — | WO | disclosed |
| US-4058604-A | OR ACARICIDALLY ACTIVE SUBSTANCES | CIBA-GEIGY AG (CH) | 1977-11-15 | — | — | US | disclosed |
| US-3988375-A | HERBICIDES | MONSANTO COMPANY (US) | 1976-10-26 | — | — | US | disclosed |
| US-3980799-A | OR ACARICIDALLY ACTIVE SUBSTANCES | CIBA-GEIGY AG (CH) | 1976-09-14 | — | — | US | disclosed |
| US-3940412-A | 2,4,5-Trichloro- and 2,4,5-tribromoimidazole derivatives and pesticidal compositions containing them | CIBA-GEIGY AG (CH) | 1976-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022521-A1 | COMPOUNDS | GRM5, GRM3, GRM1 | ALDH1A1 2931/4885CYP3A4 1629/4885MAPK1 1969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.