Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 15/20 | 0.79 |
| ▸ | MAOA | P21397 | 3/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | F10 | P00742 | 1/20 | 0.58 |
| ▸ | APP | P05067 | 1/20 | 0.57 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31114416 | 1.00 | MAOB (0.79) | MAOBMAOAGAAMAPTRAB9A | |
| SCHEMBL12533272 | 0.90 | MAOB (0.65) | MAOBMAOAGAAMAPTRAB9A | |
| 3-(Benzyloxy)Aniline SCHEMBL29428912 | 0.89 | MAOB (1.00) | MAOBMAOAGAAMAPTRAB9A | |
| 3-(Benzyloxy)Aniline SCHEMBL291445 | 0.89 | MAOB (1.00) | MAOBMAOAGAAMAPTRAB9A | |
| 3-(Benzyloxy)Aniline SCHEMBL11263814 | 0.87 | MAOB (0.96) | MAOBMAOAGAAMAPTRAB9A | |
| SCHEMBL1548932 | 0.86 | F10 (0.62) | MAOBMAOAGAAMAPTRAB9A | |
| SCHEMBL17554431 | 0.85 | LMNA (0.61) | MAOBMAOAGAAMAPTRAB9A | |
| SCHEMBL2168633 | 0.84 | MAOB (0.57) | MAOBMAOAGAAMAPTRAB9A | |
| SCHEMBL21480409 | 0.84 | MAOB (0.71) | MAOBMAOAGAAMAPTRAB9A | |
| SCHEMBL21480309 | 0.84 | MAOB (0.64) | MAOBMAOAGAAMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046445-B1 | 3-PHENOXY-METHYLENE ANILINES AS HERBICIDES, THEIR PREPARATION AND USE | CIBA-GEIGY AG (CH) | 1984-06-13 | — | — | EP | claimed |
| JP-54088231-A | — | — | None | — | — | JP | disclosed |
| EP-3901162-A1 | GLUCOCORTICOID RECEPTOR AGONIST AND IMMUNOCONJUGATES THEREOF | AbbVie Inc. (US) | 2021-10-27 | — | — | EP | disclosed |
| WO-2018068357-A1 | NOVEL SIRT2 PROTEIN INHIBITOR AND PHARMACEUTICAL USE THEREOF | 西华大学 | 2018-04-19 | — | — | WO | disclosed |
| US-8586617-B2 | Aminomethyl-4-imidazoles | HOFFMANN-LA ROCHE INC. (US) | 2013-11-19 | — | — | US | disclosed |
| CN-101528710-B | Aminomethyl-4-imidazoles | HOFFMANN LA ROCHE | 2012-11-07 | — | — | CN | disclosed |
| EP-2076497-B1 | AMINOMETHYL-4-IMIDAZOLES | HOFFMANN LA ROCHE (CH) | 2012-02-22 | — | — | EP | disclosed |
| CN-101528710-A | Aminomethyl-4-imidazoles | HOFFMANN LA ROCHE (CH) | 2009-09-09 | — | — | CN | disclosed |
| EP-2076497-A1 | AMINOMETHYL-4-IMIDAZOLES | F. Hoffmann-Roche AG (CH) | 2009-07-08 | — | — | EP | disclosed |
| US-20080119535-A1 | AMINOMETHYL-4-IMIDAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-05-22 | — | — | US | disclosed |
| WO-2008046757-A1 | AMINOMETHYL-4-IMIDAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-04-24 | — | — | WO | disclosed |
| EP-0290682-B1 | HERBICIDAL 4,5-DIHYDRO-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE DERIVATIVES | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-07-01 | — | — | EP | disclosed |
| US-4897106-A | Derivative of 4,5-dihydro-1H-1,2,4-triazole-3-carboxamide, and herbicidal composition containing the derivative | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-01-30 | — | — | US | disclosed |
| EP-0290682-A2 | Herbicidal 4,5-dihydro-1H-1,2,4-triazole-3-carboxamide derivatives | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-11-17 | — | — | EP | disclosed |
| EP-0128530-B1 | SUBSTITUTED 4,5-DIMETHOXYPYRIDAZONES, PROCESS FOR THEIR PREPARATION, HERBICIDES CONTAINING THEM AND THEIR USE IN COMBATING THE GROWTH OF UNDESIRABLE PLANTS | BASF Aktiengesellschaft (DE) | 1988-04-27 | — | — | EP | disclosed |
| EP-0091639-B1 | ANILINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN COMBATING THE GROWTH OF UNDESIRABLE PLANTS | BASF Aktiengesellschaft (DE) | 1987-06-16 | — | — | EP | disclosed |
| US-4576630-A | Substituted 4,5-dimethoxypyridazones, herbicides containing these compounds, and their use for controlling undesirable plant growth | BASF AKTIENGESELLSCHAFT (DE) | 1986-03-18 | — | — | US | disclosed |
| EP-0128530-A1 | Substituted 4,5-dimethoxypyridazones, process for their preparation, herbicides containing them and their use in combating the growth of undesirable plants | BASF Aktiengesellschaft (DE) | 1984-12-19 | — | — | EP | disclosed |
| EP-0091639-A2 | Aniline derivatives, process for their preparation and their use in combating the growth of undesirable plants | BASF Aktiengesellschaft (DE) | 1983-10-19 | — | — | EP | disclosed |
| JP-S5488231-A | 3-PHENYLOXYMETHYLANILINE DERIVATIVE, ITS PREPARATION, AND HERBICIDES CONSISTING OF IT | SUMITOMO CHEM CO LTD | 1979-07-13 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119535-A1 | AMINOMETHYL-4-IMIDAZOLES | INMT, HTR4, MC4R | MAOB 124/4885MAOA 148/4885GAA 418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.