Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Glyceryl Monostearate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.85 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.85 |
| ▸ | MEN1 | O00255 | 1/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.85 |
| ▸ | LMNA | P02545 | 1/20 | 0.85 |
| ▸ | DGKA | P23743 | 1/20 | 0.72 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.69 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.69 |
| ▸ | LPAR4 | Q99677 | 4/20 | 0.69 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.69 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.69 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.69 |
| ▸ | LPAR6 | P43657 | 2/20 | 0.69 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.64 |
| ▸ | FAAH | O00519 | 2/20 | 0.60 |
| ▸ | CES2 | O00748 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Monoctanoin Component A SCHEMBL8404946 | 0.98 | KDM4E (0.88) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Glyceryl Monostearate SCHEMBL7999761 | 0.98 | KDM4E (0.88) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Phosphoric Acid SCHEMBL28261779 | 0.98 | KDM4E (0.88) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Monoctanoin Component A SCHEMBL8808728 | 0.94 | LMNA (0.97) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Glycerin SCHEMBL2363511 | 0.94 | LMNA (0.97) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Monoctanoin Component A SCHEMBL28134044 | 0.94 | LMNA (0.97) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Glyceryl Monostearate SCHEMBL7608785 | 0.94 | LMNA (0.97) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Glycerin SCHEMBL17975822 | 0.94 | LMNA (0.97) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Glycerin SCHEMBL5929193 | 0.94 | LMNA (0.97) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Glycerin SCHEMBL3720558 | 0.94 | LMNA (0.97) | KDM4EDUSP3MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113624862-B | Metabolome covering multiple metabolites, metabolic flux analysis method and kit | 清华大学 | 2023-04-07 | — | — | CN | claimed |
| CN-113624862-B | Metabolome covering multiple metabolites, metabolic flux analysis method and kit | 清华大学 | 2023-04-07 | — | — | CN | disclosed |