Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | APAF1 | O14727 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | TDP2 | O95551 | 1/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | MPI | P34949 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2914862 | 0.85 | KDM4E (0.48) | KDM4ESMN1; SMN2MAPTAPAF1MITF | |
| SCHEMBL2908703 | 0.83 | KDM4E (0.46) | KDM4ESMN1; SMN2MAPTAPAF1MITF | |
| SCHEMBL2912119 | 0.82 | MAPT (0.45) | KDM4ESMN1; SMN2MAPTAPAF1MITF | |
| SCHEMBL2914792 | 0.81 | KDM4E (0.44) | KDM4ESMN1; SMN2MAPTAPAF1MITF | |
| SCHEMBL2905923 | 0.81 | KDM4E (0.49) | KDM4ESMN1; SMN2MAPTAPAF1MITF | |
| SCHEMBL20011497 | 0.77 | KDM4E (0.51) | KDM4ESMN1; SMN2MAPTAPAF1MITF | |
| SCHEMBL15944503 | 0.77 | ALDH1A1 (0.44) | KDM4ESMN1; SMN2MAPTAPAF1MITF | |
| SCHEMBL2913499 | 0.77 | KDM4E (0.48) | KDM4ESMN1; SMN2MAPTAPAF1MITF | |
| SCHEMBL15910477 | 0.76 | PSMB5 (0.53) | KDM4ESMN1; SMN2MAPTAPAF1MITF | |
| SCHEMBL4522982 | 0.76 | LMNA (0.50) | KDM4ESMN1; SMN2MAPTAPAF1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2223919-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND THEIR USE AS AGRICULTURAL AND HORTICULTURAL FUNGICIDES | NIPPON SODA CO (JP) | 2014-10-15 | — | — | EP | disclosed |
| EP-2223919-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND BACTERICIDE FOR AGRICULTURAL AND HORTICULTURAL USE | Nippon Soda Co., Ltd. (JP) | 2010-09-01 | — | — | EP | disclosed |