Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | MPI | P34949 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15910480 | 0.88 | LMNA (0.44) | ALDH1A1LMNAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL4522982 | 0.88 | LMNA (0.50) | ALDH1A1LMNAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL15910479 | 0.87 | LMNA (0.43) | ALDH1A1LMNAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL15910549 | 0.87 | LMNA (0.45) | ALDH1A1LMNAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL4531880 | 0.86 | CYP1A2 (0.42) | ALDH1A1LMNAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL4533531 | 0.86 | CYP1A2 (0.42) | ALDH1A1LMNAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL15910667 | 0.85 | PDGFRB (0.48) | ALDH1A1LMNAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL15910477 | 0.85 | PSMB5 (0.53) | ALDH1A1LMNAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL4507229 | 0.80 | LMNA (0.43) | ALDH1A1LMNAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL15910585 | 0.80 | LMNA (0.43) | ALDH1A1LMNAKDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9499515-B2 | Method for producing 3,4-dihydroisoquinoline derivatives and production intermediates of same | MITSUI CHEMICALS AGRO, INC. (JP) | 2016-11-22 | — | — | US | disclosed |
| US-20160039786-A1 | METHOD FOR PRODUCING 3,4-DIHYDROISOQUINOLINE DERIVATIVES AND PRODUCTION INTERMEDIATES OF SAME | MITSUI CHEMICALS AGRO, INC. (JP) | 2016-02-11 | — | — | US | disclosed |
| US-9193706-B2 | Method for producing 3,4-dihydroisoquinoline derivatives and production intermediates of same | MITSUI CHEMICALS AGRO, INC. (JP) | 2015-11-24 | — | — | US | disclosed |
| US-20140228576-A1 | METHOD FOR PRODUCING 3,4-DIHYDROISOQUINOLINE DERIVATIVES AND PRODUCTION INTERMEDIATES OF SAME | MITSUI CHEMICALS AGRO, INC. (JP) | 2014-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039786-A1 | METHOD FOR PRODUCING 3,4-DIHYDROISOQUINOLINE DERIVATIVES AND PRODUCTION INTERMEDIATES OF SAME | SDHA, NDUFS3, GOT2 | ALDH1A1 186/4885LMNA 3015/4885KDM4E 3074/4885 |
| US-20140228576-A1 | METHOD FOR PRODUCING 3,4-DIHYDROISOQUINOLINE DERIVATIVES AND PRODUCTION INTERMEDIATES OF SAME | SDHA, NDUFS3, GOT2 | ALDH1A1 186/4885LMNA 3015/4885KDM4E 3074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.