Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | BID | P55957 | 6/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 5/20 | 0.35 |
| ▸ | BAK1 | Q16611 | 5/20 | 0.35 |
| ▸ | KAT8 | Q9H7Z6 | 3/20 | 0.35 |
| ▸ | EP300 | Q09472 | 2/20 | 0.35 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.35 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | F7 | P08709 | 3/20 | 0.32 |
| ▸ | F3 | P13726 | 3/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29145355 | 0.68 | CA1 (0.35) | KDM4EMAPT | |
| SCHEMBL17471539 | 0.67 | NPC1 (0.34) | TDP1KDM4EMAPT | |
| SCHEMBL20369245 | 0.66 | ALDH1A1 (0.42) | PPARGTDP1KDM4EMAPT | |
| SCHEMBL8674815 | 0.65 | PRKCI (0.74) | PTPN1PTPN11PRKCIBIDMCL1 | |
| SCHEMBL10281157 | 0.65 | ALDH1A1 (0.43) | TDP1KDM4EMAPTALOX15HSD17B10 | |
| SCHEMBL21408322 | 0.64 | PTPN1 (0.47) | PTPN1PTPN11PRKCIBIDMCL1 | |
| SCHEMBL5192967 | 0.62 | PRKCI (0.59) | PTPN1PTPN11PRKCIBIDMCL1 | |
| SCHEMBL2129140 | 0.62 | BID (0.76) | PTPN1PTPN11BIDMCL1BCL2L1 | |
| SCHEMBL20369244 | 0.62 | ALDH1A1 (0.35) | TDP1KDM4EMAPT | |
| SCHEMBL29397743 | 0.62 | JUN (0.36) | PTPN1PTPN11PRKCIBIDMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114105888-B | Eutectic crystal of propylthiouracil and nutrient micromolecule with antioxidant activity and preparation method thereof | 天津大学 | 2023-12-01 | — | — | CN | disclosed |
| CN-114105888-A | Eutectic crystal of propylthiouracil and small nutrient molecules with antioxidant activity and preparation method thereof | 天津大学 | 2022-03-01 | — | — | CN | disclosed |