Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2918327 | 0.88 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2MAPK1TSHRHRH3 | |
| SCHEMBL2915987 | 0.85 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MAPK1TSHRHRH3 | |
| SCHEMBL8070009 | 0.81 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2MAPK1TSHRHRH3 | |
| SCHEMBL306032 | 0.81 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2MAPK1TSHRHRH3 | |
| SCHEMBL307240 | 0.80 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2MAPK1TSHRHRH3 | |
| SCHEMBL3670808 | 0.79 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2MAPK1TSHRHRH3 | |
| SCHEMBL23668758 | 0.77 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2MAPK1TSHRHRH3 | |
| SCHEMBL3677741 | 0.77 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2MAPK1TSHRHRH3 | |
| SCHEMBL12264019 | 0.77 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2MAPK1TSHRHRH3 | |
| SCHEMBL10940747 | 0.77 | SMN1; SMN2 (0.72) | ALDH1A1SMN1; SMN2MAPK1TSHRHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1388538-B1 | Polymerisation Initiator | MERCK PATENT GMBH (DE) | 2010-09-01 | — | — | EP | disclosed |
| EP-1388538-B1 | Polymerisation Initiator | MERCK PATENT GMBH (DE) | 2010-09-01 | — | — | EP | disclosed |
| EP-1388538-A1 | Polymerisation Initiator | MERCK PATENT GmbH (DE) | 2004-02-11 | — | — | EP | disclosed |