Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 5/20 | 0.36 |
| ▸ | JAK3 | P52333 | 5/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 3/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20986527 | 1.00 | NPY5R (0.36) | NPY5RLCKJAK3BTKEGFR | |
| SCHEMBL21855167 | 0.92 | JAK3 (0.41) | NPY5RLCKJAK3BTKEGFR | |
| SCHEMBL28637500 | 0.92 | JAK3 (0.41) | NPY5RLCKJAK3BTKEGFR | |
| SCHEMBL16764070 | 0.81 | FPR2 (0.49) | ALDH1A1FPR2 | |
| SCHEMBL16763648 | 0.81 | POLB (0.39) | CHRNA7HTR2ATMEM97SIGMAR1DPP4 | |
| SCHEMBL20986842 | 0.79 | CHRM3 (0.33) | CHRNA7HTR2ATMEM97SIGMAR1POLB | |
| SCHEMBL3713710 | 0.78 | KDM5A (0.44) | NPY5RJAK3BTKPOLBGAA | |
| SCHEMBL3715403 | 0.78 | KDM5A (0.44) | NPY5RJAK3BTKPOLBGAA | |
| SCHEMBL29145756 | 0.78 | KDM5A (0.44) | NPY5RJAK3BTKPOLBGAA | |
| SCHEMBL20986819 | 0.78 | ALDH1A1 (0.36) | JAK3HTR2ATMEM97SIGMAR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117480162-A | Compounds for the treatment or prophylaxis of PRMT5 mediated diseases | 阿古诺治疗有限公司 | 2024-01-30 | — | — | CN | disclosed |