Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 11/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | GSK3A | P49840 | 4/20 | 0.44 |
| ▸ | GSK3B | P49841 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | WRN | Q14191 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 5/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28787286 | 0.80 | MGLL (0.45) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL14199491 | 0.80 | MGLL (0.45) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL8161159 | 0.78 | MGLL (0.46) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL7513665 | 0.77 | MGLL (0.52) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL13985877 | 0.76 | MGLL (0.36) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL10669708 | 0.75 | PKM (0.42) | MGLLALDH1A1LMNAPKMFAAH | |
| SCHEMBL29148404 | 0.74 | MGLL (0.52) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL9468434 | 0.73 | LMNA (0.48) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL563821 | 0.73 | KMT2A (0.47) | ALDH1A1PKMHPGDMAPK1RAB9A | |
| SCHEMBL15461756 | 0.72 | MGLL (0.36) | MGLLALDH1A1BLMLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1447099-B1 | Antineoplastic polyethylene conjugates of cytostatic compounds and pharmaceuticals comprising same | KRATZ FELIX (DE) | 2008-01-09 | — | — | EP | disclosed |
| EP-1447099-A2 | Antineoplastic polyethylene conjugates of cytostatic compounds and pharmaceuticals comprising same | Kratz, Felix (DE) | 2004-08-18 | — | — | EP | disclosed |
| EP-0934081-B1 | ANTINEOPLASTIC CONJUGATES OF ALBUMIN | KRATZ FELIX (DE) | 2004-06-09 | — | — | EP | disclosed |
| US-6709679-B2 | CONSISTING OF NATIVE OR THIOLATED TRANSFERRIN OR ALBUMIN OR OF POLYETHYLENE GLYCOL WITH ATLEAST ONE MERCAPTAN, HYDROXY OR AMINE GROUP AND CYTOSTATIC COMPOUNDS DERIVED THROUGH MALEINIMIDE OR HYDROXYSUCCINIMIDE ESTER COMPOUNDS | KRATZ FELIX (DE) | 2004-03-23 | — | — | US | disclosed |
| US-20020019343-A1 | Antineoplastic conjugates of transferrin, albumin and polyethylene glycol | KRATZ FELIX (DE) | 2002-02-14 | — | — | US | disclosed |
| US-6310039-B1 | TUMOR-INHIBITING CONJUGATES OF PROTEINS AND POLYMERS CONSISTING OF A SUITABLE CARRIER SYSTEM AND CYTOSTATIC COMPOUNDS | KRATZ FELIX (DE) | 2001-10-30 | — | — | US | disclosed |
| EP-0934081-A2 | ANTINEOPLASTIC CONJUGATES OF TRANSFERRIN, ALBUMIN AND POLYETHYLENE GLYCOL | Kratz, Felix (DE) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998010794-A2 | ANTINEOPLASTIC CONJUGATES OF TRANSFERRIN, ALBUMIN AND POLYETHYLENE GLYCOL | KRATZ FELIX (DE) | 1998-03-19 | — | — | WO | disclosed |
| US-4785010-A | AGING RESISTANCE OF HUMANS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1988-11-15 | — | — | US | disclosed |
| EP-0124067-B1 | 2-(AMINOALKYL)-PYRROLE DERIVATIVES, PROCESS FOR THEIR MANUFACTURE AND THEIR USE | CASSELLA Aktiengesellschaft (DE) | 1986-12-17 | — | — | EP | disclosed |
| EP-0124067-A1 | 2-(Aminoalkyl)-pyrrole derivatives, process for their manufacture and their use | CASSELLA Aktiengesellschaft (DE) | 1984-11-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019343-A1 | Antineoplastic conjugates of transferrin, albumin and polyethylene glycol | TFRC, ALB, FOLR1 | MGLL 3432/4885ALDH1A1 2933/4885BLM 2977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.