Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 19/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.39 |
| ▸ | RET | P07949 | 2/20 | 0.39 |
| ▸ | KIT | P10721 | 2/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | FLT3 | P36888 | 2/20 | 0.39 |
| ▸ | AXL | P30530 | 2/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | ABL2 | P42684 | 1/20 | 0.39 |
| ▸ | FRK | P42685 | 1/20 | 0.39 |
| ▸ | MST1R | Q04912 | 1/20 | 0.39 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.39 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24802656 | 0.88 | MET (0.45) | METCYP3A4RETKITPDGFRA | |
| SCHEMBL30146868 | 0.88 | MET (0.45) | METCYP3A4RETKITPDGFRA | |
| SCHEMBL30785618 | 0.88 | MET (0.45) | METCYP3A4RETKITPDGFRA | |
| SCHEMBL27171642 | 0.85 | MET (0.54) | METCYP3A4RETKITPDGFRA | |
| SCHEMBL2315882 | 0.83 | KCNQ3 (0.39) | METCYP3A4KITPDGFRAKDR | |
| SCHEMBL30146806 | 0.81 | MET (0.48) | METCYP3A4RETKITPDGFRA | |
| SCHEMBL24802606 | 0.81 | MET (0.48) | METCYP3A4RETKITPDGFRA | |
| SCHEMBL4469381 | 0.80 | RAB9A (0.44) | CYP3A4KDR | |
| SCHEMBL28518969 | 0.79 | MET (0.41) | METCYP3A4RETKITPDGFRA | |
| SCHEMBL12435874 | 0.77 | KDR (0.48) | CYP3A4KITPDGFRAKDRAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117500805-A | Novel urea derivative compounds as RON inhibitors | 株式会社LG化学 | 2024-02-02 | — | — | CN | disclosed |
| CN-117500804-A | Novel urea derivative compounds as RON inhibitors | 株式会社LG化学 | 2024-02-02 | — | — | CN | disclosed |