Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29938158 | 1.00 | MAPT (0.50) | MAPTTLR8NOTUMSOS1ALDH1A1 | |
| SCHEMBL31009336 | 0.83 | MAPT (0.48) | MAPTTLR8NOTUMHTTHPGD | |
| SCHEMBL31009370 | 0.81 | NOTUM (0.49) | MAPTTLR8NOTUMHTTHPGD | |
| SCHEMBL24751455 | 0.80 | NOTUM (0.44) | MAPTTLR8NOTUMSOS1HTT | |
| SCHEMBL29149347 | 0.75 | DRD1 (0.39) | MAPTSOS1ALDH1A1HTTKDM4E | |
| SCHEMBL31009348 | 0.75 | DRD1 (0.39) | MAPTSOS1ALDH1A1HTTKDM4E | |
| SCHEMBL29938948 | 0.72 | SCN4A (0.42) | MAPTSOS1ALDH1A1HTTKDM4E | |
| SCHEMBL30078175 | 0.72 | MAPT (0.43) | MAPTTLR8NOTUMALDH1A1HTT | |
| SCHEMBL10549607 | 0.71 | L3MBTL1 (0.56) | MAPTTLR8NOTUMALDH1A1NPC1 | |
| SCHEMBL31009494 | 0.70 | ALDH1A1 (0.47) | SOS1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117500786-A | TEAD inhibitors | 奥赖恩公司 | 2024-02-02 | — | — | CN | disclosed |