SCHEMBL29149686

SCHEMBL29149686

Cc1ccc(C=CCS(=O)(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSK P43235 1/20 0.64
ALDH1A1 P00352 6/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
G6PD P11413 1/20 0.44
TLR9 Q9NR96 1/20 0.44
GAA P10253 1/20 0.43
FBP1 P09467 1/20 0.43
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
MMP1 P03956 1/20 0.41
MMP2 P08253 1/20 0.41
MMP9 P14780 1/20 0.41
MMP8 P22894 1/20 0.41
MMP13 P45452 1/20 0.41
CA12 O43570 1/20 0.41
CA3 P07451 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29149685 0.92 CTSK (0.55) CTSKALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL3379460 0.92 CTSK (0.55) CTSKALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL28585286 0.92 CTSK (0.55) CTSKALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL29149684 0.92 CTSK (0.55) CTSKALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL29169692 0.91 CTSK (0.58) CTSKALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL9620558 0.91 CTSK (0.58) CTSKALDH1A1CYP3A4CYP2C9CYP2C19
Hydrogen Sulfide SCHEMBL27733594 0.91 CTSK (0.54) CTSKALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL11038225 0.86 CTSK (0.75) CTSKALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL11278701 0.82 LMNA (0.44) CTSKMEN1KMT2AG6PDTLR9
SCHEMBL27746457 0.81 HTR2A (0.49) CTSKFBP1CA1CA2MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116969868-A Synthesis method of allyl sulfonyl compound 南通大学 2023-10-31 CN disclosed