SCHEMBL11278701

SCHEMBL11278701

Cc1ccc(C=CCS(=O)(=O)CC=Cc2ccc(C)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
NFE2L2 Q16236 2/20 0.43
CYP2A6 P11509 1/20 0.43
FBP1 P09467 1/20 0.42
ALOX5 P09917 1/20 0.42
PTGS1 P23219 1/20 0.42
PTGS2 P35354 1/20 0.42
PPARG P37231 1/20 0.42
CTSK P43235 1/20 0.42
MAPT P10636 1/20 0.41
RELA Q04206 1/20 0.41
CA1 P00915 1/20 0.41
KMT2A Q03164 2/20 0.41
RAB9A P51151 1/20 0.41
MEN1 O00255 1/20 0.41
GRIK1 P39086 1/20 0.41
GRIK2 Q13002 1/20 0.41
G6PD P11413 1/20 0.40
FOS P01100 1/20 0.39
JUN P05412 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29149686 0.82 CTSK (0.64) LMNAFBP1PTGS2CTSKCA1
SCHEMBL27918898 0.81 LMNA (0.43) LMNANFE2L2CYP2A6FBP1ALOX5
SCHEMBL10899877 0.79 AHR (0.48) NFE2L2FBP1ALOX5PTGS1PTGS2
SCHEMBL6465508 0.78 PAM (0.52) LMNANFE2L2ALOX5PPARG
SCHEMBL27572607 0.77 CA1 (0.46) LMNANFE2L2CYP2A6FBP1ALOX5
SCHEMBL3379460 0.76 CTSK (0.55) LMNAFBP1PTGS1PTGS2CTSK
SCHEMBL29149685 0.76 CTSK (0.55) LMNACTSKMAPTKMT2AMEN1
SCHEMBL28585286 0.76 CTSK (0.55) CTSKCA1KMT2AMEN1G6PD
SCHEMBL29149684 0.76 CTSK (0.55) LMNACTSKMAPTKMT2AMEN1
SCHEMBL2096660 0.76 NFE2L2 (0.48) LMNANFE2L2CYP2A6FBP1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0027421-B1 PROCESS FOR THE PREPARATION OF UNSATURATED SULPHONES, AND SULPHONES OBTAINED ANVAR Agence Nationale de Valorisation de la Recherche (FR) 1982-12-29 EP disclosed
US-4343952-A SULFONATION OF DIENE WITH SULFINATE, PALLADIUM CATALYST AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) 1982-08-10 US disclosed