Sugi Predict

Sugi Predict / Compounds / SCHEMBL29150796

SCHEMBL29150796

SCHEMBL29150796

Cc1ccc(C2=NCCC2)cn1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 1/20 0.56
▸ CYP1A2 P05177 1/20 0.56
▸ THRB P10828 1/20 0.56
▸ CYP2C19 P33261 1/20 0.56
▸ CHRNB4 P30926 12/20 0.50
▸ CHRNA3 P32297 12/20 0.50
▸ HPGDS O60760 1/20 0.40
▸ CHRNA7 P36544 3/20 0.39
▸ NPC1 O15118 1/20 0.35
▸ PKM P14618 1/20 0.35
▸ RAB9A P51151 1/20 0.35
▸ CHRNB2 P17787 1/20 0.34
▸ CHRNA4 P43681 1/20 0.34
▸ PIK3CD O00329 1/20 0.33
▸ PIK3CA P42336 1/20 0.33
▸ PIK3CB P42338 1/20 0.33
▸ PI4KA P42356 1/20 0.33
▸ PIK3CG P48736 1/20 0.33
▸ PI4KB Q9UBF8 1/20 0.33
▸ CYP11B2 P19099 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30354465 1.00 ALDH1A1 (0.56) ALDH1A1CYP1A2THRBCYP2C19CHRNB4
Trifluoroacetic Acid SCHEMBL22735410 0.85 ALDH1A1 (0.43) ALDH1A1CYP1A2THRBCYP2C19CHRNB4
SCHEMBL23992276 0.79 ALDH1A1 (0.53) ALDH1A1CYP1A2THRBCYP2C19CHRNB4
SCHEMBL24322363 0.78 ALDH1A1 (0.51) ALDH1A1CYP1A2THRBCYP2C19CHRNB4
SCHEMBL27928338 0.76 CHRNB4 (0.55) ALDH1A1CYP1A2THRBCYP2C19CHRNB4
SCHEMBL25323858 0.73 NOS3 (0.38) CHRNB4CHRNA3HPGDSCHRNA7NPC1
SCHEMBL24364973 0.73 NOS3 (0.38) CHRNB4CHRNA3HPGDSCHRNA7NPC1
SCHEMBL30470661 0.73 NOS3 (0.38) CHRNB4CHRNA3HPGDSCHRNA7NPC1
SCHEMBL676678 0.72 HPGDS (0.56) CHRNB4CHRNA3HPGDSCHRNA7NPC1
Myosmine SCHEMBL29398376 0.72 ALDH1A1 (1.00) ALDH1A1CYP1A2THRBCYP2C19CHRNB4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250270517-A1 IMINE REDUCTASE MUTANT, APPLICATION THEREOF AND APPLICATION METHOD THEREFOR ZHEJIANG ANO BIO-PHARMACEUTICAL CO., LTD. (CN) 2025-08-28 — — US claimed
EP-4592385-A1 IMINE REDUCTASE MUTANT, AND USE THEREOF AND USE METHOD THEREFOR Zhejiang Ano Bio-Pharmaceutical Co., Ltd. (CN) 2025-07-30 — — EP claimed
WO-2024152535-A1 IMINE REDUCTASE MUTANT, AND USE THEREOF AND USE METHOD THEREFOR 浙江安诺和生物医药有限公司 2024-07-25 — — WO claimed
CN-115948360-A Imine reductase mutant and application method thereof 浙江安诺和生物医药有限公司 2023-04-11 — — CN claimed
US-20250270517-A1 IMINE REDUCTASE MUTANT, APPLICATION THEREOF AND APPLICATION METHOD THEREFOR ZHEJIANG ANO BIO-PHARMACEUTICAL CO., LTD. (CN) 2025-08-28 — — US disclosed
US-20250270517-A1 IMINE REDUCTASE MUTANT, APPLICATION THEREOF AND APPLICATION METHOD THEREFOR ZHEJIANG ANO BIO-PHARMACEUTICAL CO., LTD. (CN) 2025-08-28 — — US disclosed
EP-4592385-A1 IMINE REDUCTASE MUTANT, AND USE THEREOF AND USE METHOD THEREFOR Zhejiang Ano Bio-Pharmaceutical Co., Ltd. (CN) 2025-07-30 — — EP disclosed
EP-4592385-A1 IMINE REDUCTASE MUTANT, AND USE THEREOF AND USE METHOD THEREFOR Zhejiang Ano Bio-Pharmaceutical Co., Ltd. (CN) 2025-07-30 — — EP disclosed
WO-2024152535-A1 IMINE REDUCTASE MUTANT, AND USE THEREOF AND USE METHOD THEREFOR 浙江安诺和生物医药有限公司 2024-07-25 — — WO disclosed
WO-2024152535-A1 IMINE REDUCTASE MUTANT, AND USE THEREOF AND USE METHOD THEREFOR 浙江安诺和生物医药有限公司 2024-07-25 — — WO disclosed
CN-115948360-A Imine reductase mutant and application method thereof 浙江安诺和生物医药有限公司 2023-04-11 — — CN disclosed
CN-115948360-A Imine reductase mutant and application method thereof 浙江安诺和生物医药有限公司 2023-04-11 — — CN disclosed