Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30019463 | 0.94 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL5639017 | 0.84 | NPC1 (0.49) | SMN1; SMN2ALDH1A1MAPTKDM4ENPC1 | |
| SCHEMBL3731320 | 0.78 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL30019932 | 0.77 | SYK (0.41) | SMN1; SMN2ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL29151904 | 0.77 | SYK (0.41) | SMN1; SMN2ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL5943746 | 0.74 | LMNA (0.63) | SMN1; SMN2CSNK1DALDH1A1MAPTKDM4E | |
| SCHEMBL6434460 | 0.74 | SMN1; SMN2 (0.56) | SMN1; SMN2CSNK1DALDH1A1MAPTKDM4E | |
| SCHEMBL733150 | 0.74 | GABRG2 (0.44) | SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL29581828 | 0.74 | ENPP2 (0.54) | SMN1; SMN2ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL266617 | 0.74 | ENPP2 (0.54) | SMN1; SMN2ALDH1A1MAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117529472-A | GPR35 agonist compounds | 赫普泰雅治疗有限公司 | 2024-02-06 | — | — | CN | disclosed |