Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MELK | Q14680 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922779 | 0.74 | GRM5 (0.46) | ALDH1A1MELKGRM5MMP2MMP12 | |
| SCHEMBL6446069 | 0.69 | MMP2 (0.55) | ALDH1A1MELKMMP2MMP12HTT | |
| SCHEMBL1852424 | 0.69 | PGK1 (0.34) | GRM5 | |
| SCHEMBL1852423 | 0.69 | ALDH1A1 (0.33) | ALDH1A1GRM5GAAHTT | |
| SCHEMBL29470893 | 0.67 | ALDH1A1 (0.44) | ALDH1A1MELKGRM5MMP2MMP12 | |
| SCHEMBL29154130 | 0.67 | ALDH1A1 (0.33) | ALDH1A1MELKGAAHTT | |
| SCHEMBL4853303 | 0.65 | — | — | |
| SCHEMBL2649462 | 0.65 | MMP2 (0.43) | ALDH1A1MELKMMP2MMP12 | |
| SCHEMBL6500070 | 0.65 | MELK (0.55) | ALDH1A1MELKGRM5MMP2MMP12 | |
| SCHEMBL6850648 | 0.65 | ALDH1A1 (0.57) | ALDH1A1MELKGRM5MMP2MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115989029-A | Novel compound, alpha synuclein aggregate binding agent, and use thereof | 国立研究开发法人量子科学技术研究开发机构 | 2023-04-18 | — | — | CN | disclosed |