SCHEMBL29155404

SCHEMBL29155404

NC(Cl)c1ccc(Cl)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.59
TSHR P16473 4/20 0.55
HIF1A Q16665 4/20 0.55
MAPK1 P28482 3/20 0.55
TDP1 Q9NUW8 3/20 0.55
IDO1 P14902 3/20 0.48
TDO2 P48775 3/20 0.48
LMNA P02545 3/20 0.47
CYP2A6 P11509 1/20 0.47
TP53 P04637 1/20 0.46
HPGD P15428 1/20 0.46
SLC6A4 P31645 3/20 0.44
CYP19A1 P11511 3/20 0.42
SLC6A3 Q01959 3/20 0.41
SLC6A2 P23975 2/20 0.41
CYP2C9 P11712 2/20 0.40
CYP2C19 P33261 2/20 0.40
KDM4E B2RXH2 1/20 0.40
NR1I2 O75469 1/20 0.40
ABCB11 O95342 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1732927 0.79 ADRB2 (0.62) ADRB2TSHRHIF1AMAPK1TDP1
SCHEMBL3678300 0.79 ADRB2 (0.62) ADRB2TSHRHIF1AMAPK1TDP1
SCHEMBL1155851 0.79 ADRB2 (0.62) ADRB2TSHRHIF1AMAPK1TDP1
SCHEMBL24017052 0.79 ADRB2 (0.62) ADRB2TSHRHIF1AMAPK1TDP1
SCHEMBL3253726 0.79 ADRB2 (0.62) ADRB2TSHRHIF1AMAPK1TDP1
Hydrochloric Acid SCHEMBL3179658 0.77 ADRB2 (0.59) ADRB2TSHRHIF1AMAPK1TDP1
Hydrochloric Acid SCHEMBL30098243 0.77 ADRB2 (0.59) ADRB2TSHRHIF1AMAPK1TDP1
SCHEMBL1573440 0.75 TSHR (0.60) ADRB2TSHRHIF1AMAPK1TDP1
SCHEMBL7562082 0.75 TSHR (0.60) ADRB2TSHRHIF1AMAPK1TDP1
SCHEMBL6403156 0.74 ACHE (0.44) ADRB2TDP1LMNACYP19A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117209383-B Preparation method of phenylenediamine 天津深蓝化工技术有限公司 2024-01-23 CN disclosed
CN-117209383-A Preparation method of phenylenediamine 天津深蓝化工技术有限公司 2023-12-12 CN disclosed