Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3364884 | 0.74 | POLB (0.60) | MTNR1AMTNR1BPOLBMAPTLMNA | |
| SCHEMBL578331 | 0.72 | MTNR1A (0.58) | MTNR1AMTNR1BPOLBMAPTLMNA | |
| SCHEMBL29157039 | 0.71 | MTNR1A (0.40) | MTNR1AMTNR1BMAPTPPARGPPARA | |
| SCHEMBL9130845 | 0.71 | MTNR1A (0.53) | MTNR1AMTNR1BPOLBMAPTPPARG | |
| SCHEMBL7242378 | 0.71 | PPARG (0.56) | MTNR1AMTNR1BPOLBMAPTPPARG | |
| SCHEMBL19758141 | 0.70 | LMNA (0.57) | MTNR1AMTNR1BPPARGPPARALMNA | |
| SCHEMBL8611898 | 0.70 | POLB (0.60) | MTNR1AMTNR1BPOLBMAPTLMNA | |
| SCHEMBL8611902 | 0.70 | POLB (0.56) | MTNR1AMTNR1BPOLBMAPTLMNA | |
| SCHEMBL11827528 | 0.69 | POLB (0.50) | MTNR1AMTNR1BPOLBMAPTLMNA | |
| SCHEMBL17905220 | 0.69 | LMNA (0.45) | MTNR1AMTNR1BPPARGPPARALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117377763-A | Compositions and methods for silencing MYOC expression | 阿尔尼拉姆医药品有限公司 | 2024-01-09 | — | — | CN | disclosed |