Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SCN4A | P35499 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3364884 | 0.82 | POLB (0.60) | MTNR1AMTNR1BLMNAMAPTPOLB | |
| SCHEMBL578331 | 0.81 | MTNR1A (0.58) | MTNR1AMTNR1BLMNAMAPTPOLB | |
| SCHEMBL5516567 | 0.80 | LMNA (0.51) | MTNR1AMTNR1BLMNAMAPTPOLB | |
| SCHEMBL28053099 | 0.80 | THRB (0.55) | MTNR1AMTNR1BLMNATHRBALOX15 | |
| SCHEMBL7242378 | 0.79 | PPARG (0.56) | MTNR1AMTNR1BLMNAMAPTPOLB | |
| SCHEMBL8611898 | 0.78 | POLB (0.60) | MTNR1AMTNR1BLMNAMAPTPOLB | |
| SCHEMBL8611902 | 0.78 | POLB (0.56) | MTNR1AMTNR1BLMNAMAPTPOLB | |
| SCHEMBL11259813 | 0.77 | MTNR1A (0.50) | MTNR1AMTNR1BLMNAMAPTPOLB | |
| SCHEMBL11629144 | 0.77 | POLB (0.55) | MTNR1AMTNR1BLMNAMAPTPOLB | |
| SCHEMBL11957636 | 0.77 | POLB (0.55) | MTNR1AMTNR1BLMNAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428138-A | Colorfastness, washfastness, pH sensitivity | CASSELLA AG (DE) | 1995-06-27 | — | — | US | disclosed |
| EP-0391121-B1 | Monoazo dyes, their preparation and use | CASSELLA FARBWERKE MAINKUR AG (DE) | 1994-11-23 | — | — | EP | disclosed |
| EP-0387642-B1 | Mixture of dyes | CASSELLA FARBWERKE MAINKUR AG (DE) | 1994-07-27 | — | — | EP | disclosed |
| EP-0222255-B1 | MIXTURES OF BLUE DISPERSE DYES AND THEIR USE IN DYEING POLYESTERS | CASSELLA Aktiengesellschaft (DE) | 1992-08-26 | — | — | EP | disclosed |
| US-RE33908-E | Mixtures of blue mono-azo disperse dyestuffs and their use for dyeing polyester | CASSELLA AKTIENGESELLSCHAFT (DE) | 1992-05-05 | — | — | US | disclosed |
| US-5071443-A | BLUE AZO DYESTUFF MIXTURE FOR STRONG BLUE COLOR ON HYDROPHOBIC FIBERS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1991-12-10 | — | — | US | disclosed |
| EP-0391121-A1 | Monoazo dyes, their preparation and use | CASSELLA Aktiengesellschaft (DE) | 1990-10-10 | — | — | EP | disclosed |
| US-4678476-A | HIGH TINCTORIAL STRENGTH, COLORFASTNESS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1987-07-07 | — | — | US | disclosed |
| EP-0222255-A2 | Mixtures of blue disperse dyes and their use in dyeing polyesters | CASSELLA Aktiengesellschaft (DE) | 1987-05-20 | — | — | EP | disclosed |
| EP-0031295-B1 | ORGANIC ANTIMONY-SULPHUR COMPOUNDS, THEIR USE AS STABILISERS IN CHLORIC THERMOPLASTICS, AND THERMOPLASTICS SO STABILISED | CIBA-GEIGY AG (CH) | 1983-05-18 | — | — | EP | disclosed |
| US-4367304-A | Novel organic antimony-sulfur compounds and their use as stabilizers for chlorine-containing thermoplasts | CIBA-GEIGY CORPORATION (US) | 1983-01-04 | — | — | US | disclosed |
| EP-0031295-A1 | Organic antimony-sulphur compounds, their use as stabilisers in chloric thermoplastics, and thermoplastics so stabilised | CIBA-GEIGY AG (CH) | 1981-07-01 | — | — | EP | disclosed |
| US-4066661-A | PROCESS FOR THE PREPARATION OF SUBSTITUTED TRICHLOROACETAMIDINE DERIVATIVES | MERCK & CO., INC. (US) | 1978-01-03 | — | — | US | disclosed |
| US-4065464-A | Process for the preparation of substituted trichloroacetamidine derivatives | MERCK & CO., INC. (US) | 1977-12-27 | — | — | US | disclosed |
| US-4065465-A | Process for the preparation of substituted trichloroacetamidine derivatives | MERCK & CO., INC. (US) | 1977-12-27 | — | — | US | disclosed |