SCHEMBL29157147

SCHEMBL29157147

Cc1ccc(C(=O)NC(CC(=O)O)c2ccccc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.58
TP53 P04637 1/20 0.58
UTS2R Q9UKP6 2/20 0.57
CYP26A1 O43174 3/20 0.56
KDM4E B2RXH2 1/20 0.55
GAA P10253 1/20 0.55
ROCK2 O75116 1/20 0.55
ROCK1 Q13464 1/20 0.55
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
CTSA P10619 6/20 0.53
POLB P06746 1/20 0.51
ALDH1A1 P00352 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5027698 0.89 MEN1 (0.61) LMNACYP26A1KDM4EGAAROCK2
SCHEMBL22995641 0.89 MEN1 (0.61) LMNACYP26A1KDM4EGAAROCK2
SCHEMBL3717471 0.89 MEN1 (0.61) LMNACYP26A1KDM4EGAAROCK2
SCHEMBL13947402 0.86 LMNA (0.60) LMNATP53UTS2RKDM4EGAA
SCHEMBL12302081 0.86 MAPK1 (0.66) LMNATP53UTS2RKDM4EGAA
SCHEMBL14427964 0.86 MAPK1 (0.66) LMNATP53UTS2RKDM4EGAA
SCHEMBL12302084 0.86 MAPK1 (0.66) LMNATP53UTS2RKDM4EGAA
SCHEMBL5721012 0.85 CYP26A1 (0.60) LMNATP53CYP26A1KMT2ACTSA
SCHEMBL5720878 0.85 CYP26A1 (0.60) LMNATP53CYP26A1KMT2ACTSA
SCHEMBL9830762 0.85 KDM4E (0.55) LMNAKDM4EGAAROCK2ROCK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117550987-A Method for synthesizing beta-amino acid compound based on alkene nitrogen carboxylation reaction 四川大学 2024-02-13 CN disclosed