Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | RPS6KA5 | O75582 | 3/20 | 0.52 |
| ▸ | AKT1 | P31749 | 3/20 | 0.52 |
| ▸ | GSK3B | P49841 | 3/20 | 0.52 |
| ▸ | NEK4 | P51957 | 3/20 | 0.52 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.52 |
| ▸ | PRKG2 | Q13237 | 3/20 | 0.52 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.52 |
| ▸ | PRKG1 | Q13976 | 3/20 | 0.52 |
| ▸ | PKN2 | Q16513 | 3/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22995641 | 1.00 | MEN1 (0.61) | MEN1KMT2AKDM4EGAALMNA | |
| SCHEMBL3717471 | 1.00 | MEN1 (0.61) | MEN1KMT2AKDM4EGAALMNA | |
| SCHEMBL27761114 | 0.90 | CTSA (0.62) | RPS6KA5AKT1GSK3BNEK4PRKCD | |
| SCHEMBL21274965 | 0.89 | PRNP (0.60) | MEN1KMT2AGAALMNAMAPT | |
| SCHEMBL29157147 | 0.89 | LMNA (0.58) | MEN1KMT2AKDM4EGAALMNA | |
| SCHEMBL7822835 | 0.89 | KDM4E (0.67) | KDM4EGAACYP26A1CTSAITGB3 | |
| SCHEMBL9830762 | 0.89 | KDM4E (0.55) | MEN1KMT2AKDM4EGAALMNA | |
| SCHEMBL14327771 | 0.88 | MEN1 (0.59) | MEN1KMT2AKDM4EGAALMNA | |
| SCHEMBL27553133 | 0.86 | MEN1 (0.66) | MEN1KMT2AKDM4EGAALMNA | |
| SCHEMBL5202836 | 0.86 | KDM4E (0.59) | MEN1KMT2AKDM4EGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022115488-A1 | IMMUNOGENIC NANOVESICLES FOR CANCER IMMUNOTHERAPY | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2022-06-02 | — | — | WO | disclosed |
| US-9687562-B2 | Polymers having therapeutically active agents conjugated thereto, processes of preparing same and uses thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2017-06-27 | — | — | US | disclosed |
| EP-2947111-A1 | MONOFUNCTIONAL BRANCHED POLYETHYLENEGLYCOL AND BIO-RELATED SUBSTANCE MODIFIED BY SAME | Xiamen Sinopeg Biotech Co., Ltd. (CN) | 2015-11-25 | — | — | EP | disclosed |
| WO-2015038993-A1 | NANOPARTICULATE COMPOSITIONS FOR TARGETED DELIVERY OF LIPOPHILIC DRUGS AND ACID LABILE, LIPOPHILIC PRODRUGS OF CANCER CHEMOTHERAPEUTICS AND THEIR PREPARATION | Arbor Therapeutics, LLC (US) | 2015-03-19 | — | — | WO | disclosed |
| EP-1370298-B1 | ELONGATED AND MULTIPLE SPACERS IN ACTIVATIBLE PRODRUGS | SYNTARGA BV (NL) | 2008-10-08 | — | — | EP | disclosed |
| EP-1648440-B1 | SEMI-SOLID FORMULATIONS FOR THE ORAL ADMINISTRATION OF TAXOIDS | AVENTIS PHARMA SA (FR) | 2008-03-12 | — | — | EP | disclosed |
| US-20080038785-A1 | Processes For Preparing Optically Active (S Or R-)-Beta-Amino Acid And Optically Active (R Or S)-Beta-Amino Acid Ester, And Beta-Amino Acid 2-Alkoxyethyl Ester And Optically Active (S Or R)-Beta Amino Acid 2-Alkoxyethyl Ester | UBE INDUSTRIES, LTD. (JP) | 2008-02-14 | — | — | US | disclosed |
| EP-1840218-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE (S)- OR (R)- BETA-AMINO ACIDS AND OPTICALLY ACTIVE (R)- OR (S)-BETA -AMINO ACID ESTERS, 2-ALKOXYETHYL ESTERS OF -AMINO ACIDS, AND OPTICALLY ACITVE (S)- OR (R)-2-ALKOXYETHYL ESTERS OF -AMINO ACIDS | Ube Industries, Ltd. (JP) | 2007-10-03 | — | — | EP | disclosed |