Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | RPS6KA5 | O75582 | 3/20 | 0.52 |
| ▸ | AKT1 | P31749 | 3/20 | 0.52 |
| ▸ | GSK3B | P49841 | 3/20 | 0.52 |
| ▸ | NEK4 | P51957 | 3/20 | 0.52 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.52 |
| ▸ | PRKG2 | Q13237 | 3/20 | 0.52 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.52 |
| ▸ | PRKG1 | Q13976 | 3/20 | 0.52 |
| ▸ | PKN2 | Q16513 | 3/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5027698 | 1.00 | MEN1 (0.61) | MEN1KMT2AKDM4EGAALMNA | |
| SCHEMBL3717471 | 1.00 | MEN1 (0.61) | MEN1KMT2AKDM4EGAALMNA | |
| SCHEMBL27761114 | 0.90 | CTSA (0.62) | RPS6KA5AKT1GSK3BNEK4PRKCD | |
| SCHEMBL21274965 | 0.89 | PRNP (0.60) | MEN1KMT2AGAALMNAMAPT | |
| SCHEMBL29157147 | 0.89 | LMNA (0.58) | MEN1KMT2AKDM4EGAALMNA | |
| SCHEMBL7822835 | 0.89 | KDM4E (0.67) | KDM4EGAACYP26A1CTSAITGB3 | |
| SCHEMBL9830762 | 0.89 | KDM4E (0.55) | MEN1KMT2AKDM4EGAALMNA | |
| SCHEMBL14327771 | 0.88 | MEN1 (0.59) | MEN1KMT2AKDM4EGAALMNA | |
| SCHEMBL27553133 | 0.86 | MEN1 (0.66) | MEN1KMT2AKDM4EGAALMNA | |
| SCHEMBL5202836 | 0.86 | KDM4E (0.59) | MEN1KMT2AKDM4EGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021030359-A1 | PALM FOR THE TREATMENT OF CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY INCIDENTAL TO THE TREATMENT OF CANCER | PEPTINOVO BIOPHARMA, LLC (US) | 2021-02-18 | — | — | WO | disclosed |