Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20111331 | 0.84 | HCAR2 (0.46) | HCAR2POLBALDH1A1TSHRAKR1C4 | |
| SCHEMBL28440693 | 0.78 | AKR1C2 (0.52) | HCAR2ALDH1A1TSHRSMN1; SMN2TP53 | |
| SCHEMBL392397 | 0.78 | TSHR (0.48) | HCAR2ALDH1A1TSHRSMN1; SMN2TP53 | |
| SCHEMBL659061 | 0.78 | HCAR2 (0.42) | HCAR2POLBALDH1A1TSHRAKR1C4 | |
| SCHEMBL3720517 | 0.75 | HCAR2 (0.39) | HCAR2POLBALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL31450301 | 0.75 | HCAR2 (0.39) | HCAR2POLBALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL12164567 | 0.75 | HCAR2 (0.39) | HCAR2POLBALDH1A1TSHRAKR1C4 | |
| SCHEMBL535543 | 0.75 | HAVCR2 (0.47) | HCAR2POLBALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL15758062 | 0.75 | HCAR2 (0.46) | HCAR2POLBALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7905113 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263853-A | Method for synthesizing 4-bromo-5-chloro-nicotinic acid in one step | 常州中氪生命科学技术有限公司 | 2023-12-22 | — | — | CN | claimed |
| CN-117263853-A | Method for synthesizing 4-bromo-5-chloro-nicotinic acid in one step | 常州中氪生命科学技术有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-117263853-A | Method for synthesizing 4-bromo-5-chloro-nicotinic acid in one step | 常州中氪生命科学技术有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-117263853-A | Method for synthesizing 4-bromo-5-chloro-nicotinic acid in one step | 常州中氪生命科学技术有限公司 | 2023-12-22 | — | — | CN | disclosed |