SCHEMBL392397

SCHEMBL392397

O=C(O)c1cncc(Cl)c1Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
HCAR2 Q8TDS4 4/20 0.42
ALDH1A1 P00352 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.39
TP53 P04637 1/20 0.39
CASP1 P29466 1/20 0.39
AKR1C4 P17516 1/20 0.38
AKR1C3 P42330 1/20 0.38
AKR1C2 P52895 1/20 0.38
AKR1C1 Q04828 1/20 0.38
KDM4C Q9H3R0 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
KDM6B O15054 1/20 0.36
KDM4A O75164 1/20 0.36
MAPT P10636 1/20 0.36
THRB P10828 1/20 0.36
KMT2A Q03164 1/20 0.36
KDM4D Q6B0I6 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15758062 0.88 HCAR2 (0.46) TSHRHCAR2ALDH1A1SMN1; SMN2TP53
SCHEMBL3223706 0.82 TSHR (0.34) TSHRHCAR2ALDH1A1MAPTCYP3A4
SCHEMBL28440693 0.82 AKR1C2 (0.52) TSHRHCAR2ALDH1A1SMN1; SMN2TP53
SCHEMBL2159771 0.80 ICAM1 (0.43) CASP1KMT2ATDP1CYP3A4LMNA
SCHEMBL3720517 0.78 HCAR2 (0.39) TSHRHCAR2ALDH1A1SMN1; SMN2TP53
SCHEMBL31450301 0.78 HCAR2 (0.39) TSHRHCAR2ALDH1A1SMN1; SMN2TP53
SCHEMBL3412462 0.78 GABRP (0.40) TSHRHCAR2ALDH1A1SMN1; SMN2AKR1C3
SCHEMBL2563320 0.78 KEAP1 (0.46) TSHRHCAR2ALDH1A1SMN1; SMN2TP53
SCHEMBL29157397 0.78 HCAR2 (0.39) TSHRHCAR2ALDH1A1SMN1; SMN2TP53
SCHEMBL535543 0.78 HAVCR2 (0.47) TSHRHCAR2ALDH1A1SMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 464 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119857302-B Filtering device for cleaning impurities in preparation process of dichloronicotinic acid 甘肃安隆科技有限公司 2025-05-23 CN claimed
CN-119857302-A Filtering device for cleaning impurities in preparation process of dichloronicotinic acid 甘肃安隆科技有限公司 2025-04-22 CN claimed
CN-118912845-A Drying equipment is used in dichloro nicotinic acid production 宁夏永利新材料有限公司 2024-11-08 CN claimed
CN-221693002-U Device for recycling and treating waste liquid of dichloro nicotinic acid 沈瑞雪 2024-09-13 CN claimed
CN-108404459-B Sewage pretreatment device for dichloronicotinic acid production 浙江荣凯科技发展股份有限公司 2024-06-07 CN claimed
CN-220918709-U Chlorine processing apparatus is used in dichloro nicotinic acid production 重庆增程科技有限公司 2024-05-10 CN claimed
CN-220750613-U Novel suction filtration drying device for dichloronicotinic acid 重庆增程科技有限公司 2024-04-09 CN claimed
CN-219942592-U Reaction tank capable of automatically turning materials for producing dichloronicotinic acid 重庆增程科技有限公司 2023-11-03 CN claimed
CN-219735802-U Dryer for producing dichloro nicotinic acid 江苏三鹏生物化工有限公司 2023-09-22 CN claimed
CN-219701849-U Mixed reaction kettle convenient for timely pressure release and used for dichloronicotinic acid production 重庆增程科技有限公司 2023-09-19 CN claimed
CN-207342273-U A kind of dichloro-nicotinic acid production sewage treatment filter press easy to use 浙江荣凯科技发展股份有限公司 2018-05-11 CN claimed
CN-207347310-U A kind of electrolytic processing apparatus of the dichloro-nicotinic acid production waste water of low stain 浙江荣凯科技发展股份有限公司 2018-05-11 CN claimed
CN-108002619-A It is a kind of can separation of solid and liquid dichloro-nicotinic acid production sewage treatment pot 浙江荣凯科技发展股份有限公司 2018-05-08 CN claimed
CN-107902814-A A kind of recyclable purification of waste water tank of dichloro-nicotinic acid production 浙江荣凯科技发展股份有限公司 2018-04-13 CN claimed
CN-106630383-A COD (chemical oxygen demand) degradation process for production wastewater of chloronicotinic acid 浙江荣凯科技发展股份有限公司 2017-05-10 CN claimed
CN-106630345-A Electrolytic oxidation treatment process of intermediate 2-chloronicotinic acid production wastewater 浙江荣凯科技发展股份有限公司 2017-05-10 CN claimed
CN-205773938-U A kind of dichloro-nicotinic acid produces waste water COD degeneration system 浙江荣凯科技发展股份有限公司 2016-12-07 CN claimed
CN-205687617-U A kind of dichloro-nicotinic acid production wastewater treatment system using electrolytic oxidation 浙江荣凯科技发展股份有限公司 2016-11-16 CN claimed
CN-205420240-U Mechanical device of production dichloro nicotinic acid 徐州永利精细化工有限公司 2016-08-03 CN claimed
CN-103025160-A Method for controlling sigatoka NIHON NOHYAKU CO LTD 2013-04-03 CN claimed