Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29159351 | 0.81 | SIRT2 (0.38) | KMT2AALDH1A1CA1CA2MEN1 | |
| SCHEMBL4946587 | 0.77 | KMT2A (0.59) | KMT2ASRD5A2ALDH1A1LMNACASP3 | |
| SCHEMBL11967015 | 0.73 | LMNA (0.48) | ALDH1A1LMNAPOLB | |
| SCHEMBL11967022 | 0.71 | LMNA (0.46) | LMNAPOLB | |
| SCHEMBL6051027 | 0.70 | ALOX15 (0.45) | KMT2ASRD5A2ALDH1A1LMNACASP3 | |
| SCHEMBL11967032 | 0.70 | LMNA (0.43) | ALDH1A1LMNAPOLB | |
| SCHEMBL29145870 | 0.69 | KMT2A (0.51) | KMT2ASRD5A2ALDH1A1LMNACASP3 | |
| SCHEMBL2449453 | 0.67 | TDP1 (0.62) | KMT2AALDH1A1LMNATDP1PKM | |
| SCHEMBL8120865 | 0.67 | TDP1 (0.62) | KMT2AALDH1A1LMNATDP1PKM | |
| SCHEMBL8121266 | 0.67 | TDP1 (0.62) | KMT2AALDH1A1LMNATDP1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069793-A | Bifunctional linker compound, antibody drug conjugate, and preparation methods and applications thereof | 杭州爱科瑞思生物医药有限公司 | 2023-11-17 | — | — | CN | disclosed |