Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12552172 | 0.95 | MPO (0.43) | MPOALDH1A1POLBLMNAKDM5B | |
| SCHEMBL25699980 | 0.79 | ALDH1A1 (0.45) | ALDH1A1POLBLMNAKDM5BKMT2A | |
| SCHEMBL29159667 | 0.79 | ALDH1A1 (0.42) | ALDH1A1POLBLMNAKDM5BKMT2A | |
| SCHEMBL28941507 | 0.78 | MPO (0.43) | MPO | |
| SCHEMBL20661128 | 0.77 | KDM5B (0.43) | ALDH1A1POLBLMNAKDM5BPI4KA | |
| SCHEMBL25478019 | 0.76 | KDM5B (0.43) | ALDH1A1POLBLMNAKDM5BKMT2A | |
| SCHEMBL20237038 | 0.75 | KDM5B (0.40) | ALDH1A1POLBLMNAKDM5BKMT2A | |
| SCHEMBL21962281 | 0.75 | CYP4F2 (0.40) | ALDH1A1POLBLMNAKDM5BKMT2A | |
| SCHEMBL16353569 | 0.75 | ALDH1A1 (0.44) | ALDH1A1POLBLMNAKDM5BKMT2A | |
| SCHEMBL1128591 | 0.75 | KDM5B (0.40) | ALDH1A1POLBLMNAKDM5BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117580824-A | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2024-02-20 | — | — | CN | disclosed |