Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 2/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29159596 | 0.95 | MPO (0.44) | MPOKDM5BALDH1A1LMNAPOLB | |
| SCHEMBL20661128 | 0.82 | KDM5B (0.43) | KDM5BALDH1A1LMNAPOLBCYP4F2 | |
| SCHEMBL584036 | 0.80 | KDM5B (0.40) | KDM5BALDH1A1LMNAPOLBCYP4F2 | |
| SCHEMBL1565909 | 0.80 | KDM5B (0.42) | KDM5BALDH1A1LMNAPOLBCYP4F2 | |
| SCHEMBL1128591 | 0.80 | KDM5B (0.40) | KDM5BALDH1A1LMNAPOLBCYP4F2 | |
| SCHEMBL20380105 | 0.80 | KDM5B (0.40) | KDM5BALDH1A1LMNAPOLBCYP4F2 | |
| SCHEMBL16353569 | 0.80 | ALDH1A1 (0.44) | KDM5BALDH1A1LMNAPOLBCYP4F2 | |
| SCHEMBL21962281 | 0.80 | CYP4F2 (0.40) | KDM5BALDH1A1LMNAPOLBCYP4F2 | |
| SCHEMBL20237038 | 0.80 | KDM5B (0.40) | KDM5BALDH1A1LMNAPOLBCYP4F2 | |
| SCHEMBL15607370 | 0.80 | KDM5B (0.40) | KDM5BALDH1A1LMNAPOLBCYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12528831-B1 | Layered metal-organic framework material and preparation method and use thereof | BEIJING UNIVERSITY OF TECHNOLOGY (CN) | 2026-01-20 | — | — | US | claimed |
| CN-117659430-B | Layered metal organic framework material, preparation method and application | 北京工业大学 | 2025-06-17 | — | — | CN | claimed |
| CN-119490480-A | Isophenyl bridged alkynyl pyrazole pyridine derivative and preparation method and application thereof | 北京工业大学 | 2025-02-21 | — | — | CN | claimed |
| CN-117659430-A | Layered metal organic framework material, preparation method and application | 北京工业大学 | 2024-03-08 | — | — | CN | claimed |
| WO-2026105055-A1 | INHIBITORS OF CANINE JANUS KINASE AND USES THEREOF | ANIMOL DISCOVERY, INC (US) | 2026-05-21 | — | — | WO | disclosed |
| US-20260116881-A1 | KIF MODULATOR COMPOUNDS AND METHODS OF USE | IAMBIC THERAPEUTICS INC (US) | 2026-04-30 | — | — | US | disclosed |
| US-20260085061-A1 | PHTHALAZINE DERIVATIVES AS PYRUVATE KINASE MODULATORS | SITRYX THERAPEUTICS LIMITED (GB) | 2026-03-26 | — | — | US | disclosed |
| US-12528831-B1 | Layered metal-organic framework material and preparation method and use thereof | BEIJING UNIVERSITY OF TECHNOLOGY (CN) | 2026-01-20 | — | — | US | disclosed |
| US-12448367-B2 | Phthalazine derivatives as pyruvate kinase modulators | SITRYX THERAPEUTICS LIMITED (GB) | 2025-10-21 | — | — | US | disclosed |
| EP-4612132-A1 | PHTHALAZINE DERIVATIVES AS PYRUVATE KINASE MODULATORS | Sitryx Therapeutics Limited (GB) | 2025-09-10 | — | — | EP | disclosed |
| US-12404261-B2 | Compounds and compositions for treating conditions associated with cGAS | NOVARTIS AG (CH) | 2025-09-02 | — | — | US | disclosed |
| EP-3980412-B1 | 1-PYRAZOLYL, 5-, 6- DISUBSTITUTED INDAZOLE DERIVATIVES AS LRRK2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2025-08-13 | — | — | EP | disclosed |
| US-20160038486-A1 | DRUG FOR RESPIRATORY DISEASES | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-02-11 | — | — | US | disclosed |
| EP-2974730-A1 | DRUG FOR RESPIRATORY DISEASES | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-01-20 | — | — | EP | disclosed |
| EP-2813491-A1 | CYCLOALKANE DERIVATIVE | Daiichi Sankyo Co., Ltd. (JP) | 2014-12-17 | — | — | EP | disclosed |
| US-8889741-B2 | Cycloalkane derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-11-18 | — | — | US | disclosed |
| US-20140045862-A1 | Cycloalkane Derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-02-13 | — | — | US | disclosed |
| EP-2299824-B1 | PYRAZOLE DERIVATIVES USEFUL AS INHIBITORS OF FAAH | MERCK SHARP & DOHME (US) | 2013-06-19 | — | — | EP | disclosed |
| US-20110144056-A1 | PYRAZOLE DERIVATIVES USEFUL AS INHIBITORS OF FAAH | MERCK SHARP & DOHME CORP. | 2011-06-16 | — | — | US | disclosed |
| US-20110144056-A1 | PYRAZOLE DERIVATIVES USEFUL AS INHIBITORS OF FAAH | MERCK SHARP & DOHME CORP. | 2011-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260116881-A1 | KIF MODULATOR COMPOUNDS AND METHODS OF USE | KIF2C, KIF5B, KIF5C | MPO 4731/4885KDM5B 2611/4885ALDH1A1 2556/4885 |
| US-12404261-B2 | Compounds and compositions for treating conditions associated with cGAS | CGAS, TDP1, IAPP | MPO 233/4885KDM5B 4786/4885ALDH1A1 2159/4885 |
| US-20260085061-A1 | PHTHALAZINE DERIVATIVES AS PYRUVATE KINASE MODULATORS | PDK1, PDK2, PDK4 | MPO 3489/4885KDM5B 1311/4885ALDH1A1 629/4885 |
| US-20110144056-A1 | PYRAZOLE DERIVATIVES USEFUL AS INHIBITORS OF FAAH | FAAH, FAAH2, HRH2 | MPO 3518/4885KDM5B 755/4885ALDH1A1 1185/4885 |
| US-20160038486-A1 | DRUG FOR RESPIRATORY DISEASES | SCN1B, NHERF1, SCNN1A | MPO 1845/4885KDM5B 4800/4885ALDH1A1 641/4885 |
| US-20140045862-A1 | Cycloalkane Derivatives | TRPV1, TRPA1, SCNN1A | MPO 1590/4885KDM5B 4754/4885ALDH1A1 718/4885 |
| US-12528831-B1 | Layered metal-organic framework material and preparation method and use thereof | HAO2, CTNND1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | MPO 636/4885KDM5B 1677/4885ALDH1A1 3223/4885 |
| US-12448367-B2 | Phthalazine derivatives as pyruvate kinase modulators | PDK1, PDK2, PDK3 | MPO 3328/4885KDM5B 1880/4885ALDH1A1 1062/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.