Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F11 | P03951 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
| ▸ | SLC9A5 | Q14940 | 1/20 | 0.32 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24819195 | 0.77 | LMNA (0.36) | LMNAMAPT | |
| SCHEMBL30050646 | 0.77 | LMNA (0.36) | LMNAMAPT | |
| SCHEMBL22721749 | 0.74 | F11 (0.38) | F2F11PRSS1PRSS2PRSS3 | |
| SCHEMBL29159710 | 0.74 | PARP1 (0.35) | F2F11PRSS1PRSS2PRSS3 | |
| SCHEMBL27212329 | 0.74 | F2 (0.30) | F2F11PRSS1PRSS2PRSS3 | |
| SCHEMBL29159708 | 0.73 | KDM4E (0.37) | LMNAMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL28934355 | 0.72 | HIF1A (0.36) | F2F11PRSS1PRSS2PRSS3 | |
| SCHEMBL29178922 | 0.72 | MAPK1 (0.35) | LMNAMAPT | |
| SCHEMBL24822117 | 0.71 | AAK1 (0.38) | LMNA | |
| SCHEMBL29208186 | 0.71 | KDM4E (0.42) | LMNAMAPTKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117580849-A | Steroid compound, pharmaceutical composition and application thereof | 江苏先声药业有限公司 | 2024-02-20 | — | — | CN | disclosed |