Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | F11 | P03951 | 3/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28607887 | 0.83 | UCHL1 (0.41) | CA1CA2CA9UCHL1MEN1 | |
| SCHEMBL22721749 | 0.82 | F11 (0.38) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL15334799 | 0.80 | ACHE (0.47) | CSF1RACHEUCHL1NPSR1MEN1 | |
| SCHEMBL5762336 | 0.78 | JAK2 (0.37) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL28811736 | 0.76 | F2 (0.32) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL28597856 | 0.75 | MEN1 (0.41) | HIF1AF11F2PRSS1PRSS2 | |
| SCHEMBL29276164 | 0.75 | ALDH1A1 (0.37) | CSF1RACHENPSR1MEN1KMT2A | |
| SCHEMBL28870982 | 0.74 | MEN1 (0.40) | HIF1AF11F2PRSS1PRSS2 | |
| SCHEMBL29175545 | 0.74 | UCHL1 (0.34) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL28736211 | 0.74 | LIPG (0.36) | F11F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115433163-A | NLRP3 inflammasome inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2022-12-06 | — | — | CN | disclosed |