Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | SPR | P35270 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20120108 | 0.93 | KDM4E (0.50) | EGFRKDM4EPOLBHSD17B10L3MBTL1 | |
| SCHEMBL29160660 | 0.85 | SPR (0.50) | KDM4EPOLBHSD17B10L3MBTL1SPR | |
| SCHEMBL12923716 | 0.85 | PLA2G4A (0.54) | EGFRKDM4EHSD17B10PLA2G4APPARG | |
| SCHEMBL29123527 | 0.84 | PLA2G2A (0.46) | EGFRKDM4EPOLBHSD17B10L3MBTL1 | |
| SCHEMBL18269292 | 0.84 | EGFR (0.47) | EGFRKDM4EPOLBHSD17B10L3MBTL1 | |
| SCHEMBL34461880 | 0.84 | EGFR (0.47) | EGFRKDM4EHSD17B10PLA2G4ASPR | |
| SCHEMBL18271582 | 0.84 | AKR1C3 (0.56) | KDM4EHSD17B10MEN1KMT2ALMNA | |
| Benzamide SCHEMBL29160658 | 0.82 | PLA2G2A (0.44) | EGFRKDM4EPOLBHSD17B10PLA2G4A | |
| SCHEMBL29160657 | 0.82 | NPC1 (0.53) | KDM4EPOLBSPRMEN1KMT2A | |
| SCHEMBL18509721 | 0.82 | SPR (0.42) | KDM4EPOLBHSD17B10L3MBTL1SPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117567349-A | Design synthesis and anti-tumor activity research of novel indole structure-containing drug small molecules | 长春工业大学 | 2024-02-20 | — | — | CN | disclosed |