SCHEMBL29161128

SCHEMBL29161128

C=CC(=O)OCCCC(I)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.51
TSHR P16473 7/20 0.47
ALDH1A1 P00352 3/20 0.47
CYP3A4 P08684 1/20 0.47
HPGD P15428 1/20 0.44
TP53 P04637 2/20 0.40
HIF1A Q16665 2/20 0.40
HSD17B10 Q99714 1/20 0.40
CYP2C19 P33261 1/20 0.37
TDP1 Q9NUW8 2/20 0.37
HCAR2 Q8TDS4 1/20 0.35
CHRNB2 P17787 1/20 0.35
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
CHRNA4 P43681 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
AKR1B10 O60218 1/20 0.35
AKR1B1 P15121 1/20 0.35
NPC1 O15118 1/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29161102 0.96 TSHR (0.50) THRBTSHRALDH1A1CYP3A4HPGD
SCHEMBL15901529 0.86 THRB (0.55) THRBTSHRALDH1A1CYP3A4HPGD
SCHEMBL25385324 0.82 THRB (0.51) THRBTSHRALDH1A1CYP3A4HPGD
SCHEMBL22047091 0.82 THRB (0.51) THRBTSHRALDH1A1CYP3A4HPGD
SCHEMBL24709495 0.81 THRB (0.60) THRBTSHRALDH1A1CYP3A4HPGD
SCHEMBL28362790 0.80 LMNA (0.54) CYP2C19TDP1CHRNB2CHRNB4CHRNA3
SCHEMBL10457516 0.80 THRB (0.49) THRBTSHRALDH1A1CYP3A4HPGD
SCHEMBL21837194 0.79 CHRNB2 (0.57) THRBTSHRALDH1A1CYP3A4HPGD
Hydrochloric Acid SCHEMBL19281720 0.78 CHRNB2 (0.56) THRBTSHRALDH1A1CYP3A4HPGD
SCHEMBL15361864 0.78 THRB (0.47) THRBTSHRALDH1A1CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117586645-A Coloring composition containing dioxazine pigment and color filter 大塚化学株式会社 2024-02-23 CN disclosed