Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 10/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27873246 | 0.83 | ALOX5 (0.35) | ALOX5PTGS2HTR2ACYP1A2 | |
| SCHEMBL12514803 | 0.81 | TPMT (0.38) | PTGS2HTR2AMEN1ALDH1A1TP53 | |
| SCHEMBL26036404 | 0.77 | TYR (0.37) | ALOX5TYRMEN1ALDH1A1TP53 | |
| SCHEMBL1530694 | 0.73 | TTR (0.48) | PTGS2ALDH1A1CYP3A4MAPK1 | |
| SCHEMBL28187609 | 0.73 | ACHE (0.41) | ALOX5PTGS2HTR2ATYRALDH1A1 | |
| SCHEMBL20226039 | 0.73 | PTGS2 (0.44) | ALOX5PTGS2HTR2ACYP3A4HPGD | |
| SCHEMBL25922512 | 0.72 | HTT (0.42) | ALOX5TYRMEN1ALDH1A1TP53 | |
| SCHEMBL1599821 | 0.72 | ALOX5 (0.59) | ALOX5PTGS2TYRCYP3A4 | |
| SCHEMBL19122669 | 0.71 | HTR2A (0.43) | ALOX5PTGS2HTR2A | |
| SCHEMBL28042367 | 0.71 | ALOX5 (0.41) | ALOX5PTGS2HTR2ACNR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |