SCHEMBL2916191

SCHEMBL2916191

CCc1cc(CCCO)cc(C2(C)CCCCC2)c1O

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.45
TSHR P16473 1/20 0.45
ALOX12 P18054 1/20 0.45
NPSR1 Q6W5P4 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
ATM Q13315 1/20 0.40
HSD17B10 Q99714 1/20 0.40
TP53 P04637 1/20 0.37
GAA P10253 1/20 0.37
TNKS2 Q9H2K2 1/20 0.36
RARB P10826 2/20 0.34
RARG P13631 2/20 0.34
PTGDR Q13258 1/20 0.32
PTGDR2 Q9Y5Y4 1/20 0.32
RARA P10276 1/20 0.30
BCHE P06276 2/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3808966 0.92 GLA (0.47) GLATSHRALOX12NPSR1MEN1
SCHEMBL13899762 0.90 GLA (0.46) GLATSHRALOX12NPSR1MEN1
SCHEMBL14003069 0.89 GLA (0.44) GLATSHRALOX12NPSR1MEN1
SCHEMBL13899765 0.86 GLA (0.45) GLATSHRALOX12NPSR1MEN1
SCHEMBL14002989 0.86 GLA (0.41) GLATSHRALOX12NPSR1MEN1
SCHEMBL13899735 0.85 GLA (0.44) GLATSHRALOX12NPSR1MEN1
SCHEMBL13899760 0.85 GLA (0.44) GLATSHRALOX12NPSR1MEN1
SCHEMBL2911296 0.83 GLA (0.44) GLATSHRALOX12NPSR1MEN1
SCHEMBL7944733 0.83 TNKS2 (0.37) GLATSHRALOX12TNKS2RARB
SCHEMBL14002990 0.83 TNKS2 (0.40) GLATSHRALOX12NPSR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2110370-B1 Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL CO (JP) 2010-09-01 EP disclosed
EP-1348686-B1 Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL CO (JP) 2010-03-03 EP disclosed
EP-2110370-A1 Method of producing p-hydroxyphenylalkanols Sumitomo Chemical Company, Limited (JP) 2009-10-21 EP disclosed
CN-1572795-A Process for producing phosphite SUMITOMO CHEMICAL CO (JP) 2005-02-02 CN disclosed
EP-1484334-A2 Process for producing phosphite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-08 EP disclosed
US-20040225145-A1 Process for producing phosphite SUMITOMO CHEMICAL COMPANY, LIMITED 2004-11-11 US disclosed
US-6717020-B2 HIGH YIELD REACTION OF PHENOLS AND UNSATURATED ALCOHOLS IN PRESENCE OF SUCH AS TITANIUM TETRAETHOXIDE AND SODIUM METHOXIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-04-06 US disclosed
US-20030195379-A1 Method of producing p-Hydroxyphenylalkanols SUMITOMO CHEMICAL COMPANY, LIMITED 2003-10-16 US disclosed
EP-1348686-A1 Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-10-01 EP disclosed
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030195379-A1 Method of producing p-Hydroxyphenylalkanols ADH1C, NR1H3, ADH5 GLA 2173/4885TSHR 1925/4885ALOX12 631/4885
US-20040225145-A1 Process for producing phosphite PHOSPHO1, PLCG1, PLCG2 GLA 1638/4885TSHR 2144/4885ALOX12 510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.