SCHEMBL7944733

SCHEMBL7944733

CCc1cc(CCCO)cc(C2(C)CCCCC2)c1OC

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TNKS2 Q9H2K2 1/20 0.37
RARA P10276 2/20 0.34
RARB P10826 2/20 0.34
RARG P13631 2/20 0.34
FASN P49327 1/20 0.34
CNR2 P34972 7/20 0.32
PTGDR Q13258 1/20 0.32
PTGDR2 Q9Y5Y4 1/20 0.32
GLA P06280 1/20 0.32
TSHR P16473 1/20 0.32
ALOX12 P18054 1/20 0.32
MAPT P10636 1/20 0.32
ALOX15 P16050 1/20 0.32
CYP4A11 Q02928 2/20 0.31
S1PR1 P21453 1/20 0.31
CYP4F2 P78329 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6568848 0.92 RARB (0.36) RARARARBRARGPTGDRPTGDR2
SCHEMBL7944933 0.85 TNKS2 (0.38) TNKS2RARARARBRARGFASN
SCHEMBL6568837 0.84 CNR2 (0.34) RARARARBRARGCNR2GLA
SCHEMBL7796429 0.84 CYP26B1 (0.41) RARARARBRARGPTGDRPTGDR2
SCHEMBL2916191 0.83 GLA (0.45) TNKS2RARARARBRARGPTGDR
SCHEMBL7941069 0.83 ALDH1A1 (0.37) RARARARBRARGCYP4A11S1PR1
SCHEMBL6567008 0.81 TNKS2 (0.36) TNKS2RARARARBRARG
SCHEMBL7792167 0.81 PTGDR (0.43) RARARARBRARGPTGDRPTGDR2
SCHEMBL8400745 0.80 KMT2A (0.40) RARARARBRARGPTGDRPTGDR2
SCHEMBL8400744 0.78 RARA (0.34) RARARARBRARGPTGDRPTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed