Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HAVCR2 | Q8TDQ0 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24807308 | 0.84 | MAT2A (0.63) | MAT2AKDM4EMEN1CASP1KMT2A | |
| SCHEMBL24807286 | 0.78 | MAT2A (0.50) | MAT2AKDM4EMEN1CASP1KMT2A | |
| SCHEMBL29162191 | 0.78 | MAT2A (0.50) | MAT2AKDM4EMEN1CASP1KMT2A | |
| SCHEMBL29162211 | 0.78 | MAT2A (0.41) | MAT2APTGES | |
| SCHEMBL24807047 | 0.74 | MAT2A (0.62) | MAT2AKDM4EMEN1CASP1KMT2A | |
| SCHEMBL24807057 | 0.73 | MAT2A (0.51) | MAT2AKDM4EMEN1CASP1KMT2A | |
| SCHEMBL29162209 | 0.70 | MAT2A (0.40) | MAT2A | |
| SCHEMBL30639628 | 0.69 | MAT2A (1.00) | MAT2AKDM4EMEN1CASP1KMT2A | |
| SCHEMBL23601321 | 0.68 | EGFR (0.42) | MAT2A | |
| SCHEMBL29141395 | 0.68 | EGFR (0.42) | MAT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117480155-A | Diacylglycerol kinase modulating compounds | 吉利德科学公司 | 2024-01-30 | — | — | CN | disclosed |