Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HAVCR2 | Q8TDQ0 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29162198 | 0.84 | KDM4E (0.33) | MAT2AKDM4ESMN1; SMN2LMNA | |
| SCHEMBL29210707 | 0.79 | SOS1 (0.30) | — | |
| SCHEMBL24808651 | 0.79 | MAT2A (0.49) | MAT2AKDM4EMEN1CASP1KMT2A | |
| SCHEMBL29162195 | 0.78 | MAT2A (0.51) | MAT2AKDM4EMEN1CASP1KMT2A | |
| SCHEMBL29162209 | 0.78 | MAT2A (0.40) | MAT2A | |
| SCHEMBL29210705 | 0.75 | GAA (0.34) | — | |
| SCHEMBL24807047 | 0.73 | MAT2A (0.62) | MAT2AKDM4EMEN1CASP1KMT2A | |
| SCHEMBL24807057 | 0.72 | MAT2A (0.51) | MAT2AKDM4EMEN1CASP1KMT2A | |
| SCHEMBL29162211 | 0.69 | MAT2A (0.41) | MAT2A | |
| SCHEMBL30639628 | 0.68 | MAT2A (1.00) | MAT2AKDM4EMEN1CASP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117480155-A | Diacylglycerol kinase modulating compounds | 吉利德科学公司 | 2024-01-30 | — | — | CN | disclosed |