Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MPO | P05164 | 1/20 | 0.30 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | MAT2A | P31153 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29162191 | 0.84 | MAT2A (0.50) | KDM4ELMNASMN1; SMN2MAT2A | |
| SCHEMBL30095575 | 0.77 | AR (0.35) | KDM4EALDH1A1GLAGAAHTT | |
| SCHEMBL24807299 | 0.77 | AR (0.35) | KDM4EALDH1A1GLAGAAHTT | |
| SCHEMBL29162194 | 0.77 | — | — | |
| SCHEMBL24808395 | 0.70 | AR (0.34) | KDM4EALDH1A1GLAGAAHTT | |
| SCHEMBL29210707 | 0.68 | SOS1 (0.30) | — | |
| SCHEMBL29210705 | 0.65 | GAA (0.34) | GAA | |
| SCHEMBL24807300 | 0.65 | AR (0.40) | KEAP1NFE2L2LMNASMN1; SMN2 | |
| SCHEMBL30095637 | 0.64 | — | — | |
| SCHEMBL10746430 | 0.63 | KEAP1 (0.56) | KDM4EALDH1A1GLAGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117480155-A | Diacylglycerol kinase modulating compounds | 吉利德科学公司 | 2024-01-30 | — | — | CN | disclosed |