Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPY4R | P50391 | 14/20 | 0.41 |
| ▸ | NPY1R | P25929 | 9/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.41 |
| ▸ | NPY2R | P49146 | 5/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 2/20 | 0.38 |
| ▸ | MC3R | P41968 | 2/20 | 0.38 |
| ▸ | MC1R | Q01726 | 2/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29164081 | 0.93 | IDE (0.43) | SMN1; SMN2NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29164082 | 0.88 | F2 (0.43) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29163540 | 0.88 | SMN1; SMN2 (0.39) | LMNASMN1; SMN2NPY4RNPY1RNPY5R | |
| Pabetan SCHEMBL29894618 | 0.83 | NPY4R (0.46) | NPY4RNPY1RNPY5RNPY2RCTSD | |
| Pabetan SCHEMBL21571465 | 0.83 | NPY4R (0.46) | NPY4RNPY1RNPY5RNPY2RCTSD | |
| Pabetan SCHEMBL4546522 | 0.83 | NPY4R (0.46) | NPY4RNPY1RNPY5RNPY2RCTSD | |
| Pabetan SCHEMBL14928984 | 0.83 | NPY4R (0.46) | NPY4RNPY1RNPY5RNPY2RCTSD | |
| SCHEMBL8342382 | 0.82 | MEN1 (0.43) | LMNAMAPTSMN1; SMN2NPY4RNPY1R | |
| Hydrochloric Acid SCHEMBL28274778 | 0.81 | MEN1 (0.43) | LMNAMAPTSMN1; SMN2NPY4RNPY1R | |
| Hydrochloric Acid SCHEMBL28274785 | 0.81 | MEN1 (0.43) | LMNAMAPTSMN1; SMN2NPY4RNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486762-A | Novel compound and use method and application thereof | 中国医学科学院医药生物技术研究所 | 2024-02-02 | — | — | CN | disclosed |